Rabbit anti-Human, Mouse STK17A Polyclonal Antibody | anti-STK17A antibody

STK17A Rabbit Polyclonal

Cat. Num. AAA7604559

• Gene Names: STK17A; DRAK1
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: STK17A; Polyclonal Antibody; STK17A Rabbit Polyclonal; anti-STK17A antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 414

• Applicable Applications for anti-STK17A antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Serine/threonine kinase 17a
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human heart using MBS7604559 (STK17A antibody) at dilution of 1:50)

Western Blot (WB)

(BxPC-3 cells were subjected to SDS PAGE followed by western blot with MBS7604559 (STK17A antibody) at dilution of 1:2000)

NCBI and Uniprot Product Information

• NCBI GI #: 109255245
• NCBI GeneID: 9263
• NCBI Accession #: NP_004751.2
• NCBI GenBank Nucleotide #: NM_004760.2
• Molecular Weight: 46,558 Da
• NCBI Official Full Name: serine/threonine-protein kinase 17A
• NCBI Official Synonym Full Names: serine/threonine kinase 17a
• NCBI Official Symbol: STK17A
• NCBI Official Synonym Symbols: DRAK1
• NCBI Protein Information: serine/threonine-protein kinase 17A
• UniProt Protein Name: Serine/threonine-protein kinase 17A
• Protein Family: Serine/threonine-protein kinase
• UniProt Gene Name: STK17A
• UniProt Synonym Gene Names: DRAK1
• UniProt Entry Name: ST17A_HUMAN

NCBI Description

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]

Uniprot Description

DRAK1: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleus

Molecular Function: ATP binding; protein serine/threonine kinase activity

Biological Process: apoptosis; positive regulation of apoptosis; protein amino acid phosphorylation