Western Blot (WB)
(Western blot analysis STAP-2 using HT-29 whole cell lysates)
Rabbit anti-Human STAP-2 Polyclonal Antibody | anti-STAP-2 antibody
STAP-2 Antibody
Gene Names
STAP2; BKS
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
STAP-2; Polyclonal Antibody; STAP-2 Antibody; BKS; Breast tumor kinase substrate; Brk kinase substrate; BRK substrate; Signal transducing adaptor protein 2; Signal-transducing adaptor protein 2; Ssignal transducing adaptor family member 2; STAP 2; STAP2; STAP2_HUMAN; anti-STAP-2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
STAP-2 antibody detects endogenous levels of total STAP-2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
403
Applicable Applications for anti-STAP-2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human STAP-2
Subcellular Location
Cytoplasm.
Tissue Specificity
Widely expressed.
Predicted Cross Reactivity
Pig, Bovine, Sheep, Dog
Similarity
Pig (89%), Bovine (100%), Sheep (89%), Dog (89%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis STAP-2 using HT-29 whole cell lysates)
Western Blot (WB)
(Western blot analysis STAP-2 using HT-29 whole cell lysates)
Related Product Information for anti-STAP-2 antibody
Function: Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.
Subunit Structure: Interacts with PTK6 and CSF1R.
Post-translational Modifications: Phosphorylated on tyrosine. Tyr-250 may be important for interaction with kinases. Phosphorylated by PTK6 at Tyr-250 modulates PTK6-mediated STAT3 activation. Tyr-22 and Tyr-322 appears to be phosphorylated by SRC.
Subunit Structure: Interacts with PTK6 and CSF1R.
Post-translational Modifications: Phosphorylated on tyrosine. Tyr-250 may be important for interaction with kinases. Phosphorylated by PTK6 at Tyr-250 modulates PTK6-mediated STAT3 activation. Tyr-22 and Tyr-322 appears to be phosphorylated by SRC.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 45 kDa
Predicted: 45 kDa
Predicted: 45 kDa
NCBI Official Full Name
signal-transducing adaptor protein 2 isoform 2
NCBI Official Synonym Full Names
signal transducing adaptor family member 2
NCBI Official Symbol
STAP2
NCBI Official Synonym Symbols
BKS
NCBI Protein Information
signal-transducing adaptor protein 2
UniProt Protein Name
Signal-transducing adaptor protein 2
UniProt Gene Name
STAP2
UniProt Synonym Gene Names
BKS; STAP-2; BRK substrate
NCBI Description
This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Uniprot Description
Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.
Research Articles on STAP-2
Similar Products
Product Notes
The STAP-2 stap2 (Catalog #AAA9602944) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STAP-2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STAP-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the STAP-2 stap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STAP-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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