Related Product Information for anti-STAG1 antibody
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.
Product Categories/Family for anti-STAG1 antibody
References
Chasman, D.I., et al. PLoS Genet. 5 (11), E1000730 (2009): Canudas, S., et al. J. Cell Biol. 187(2):165-173(2009). Rubio, E.D., et al. Proc. Natl. Acad. Sci. U.S.A. 105(24):8309-8314(2008). Watrin, E., et al. Curr. Biol. 16(9):863-874(2006). Losada, A., et al. J. Cell. Sci. 118 (PT 10), 2133-2141 (2005).
NCBI Description
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008]
Uniprot Description
STAG1: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Belongs to the SCC3 family.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 3q22.3
Cellular Component: nucleoplasm; chromosome; nucleus; cytosol; chromatin; chromosome, pericentric region
Molecular Function: protein binding; chromatin binding
Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation
Product Notes
The STAG1 stag1 (Catalog #
AAA6351655) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STAG1, ID (STAG1, SA1, Cohesin subunit SA-1, SCC3 homolog 1, Stromal antigen 1) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STAG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the STAG1 stag1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"STAG1, Polyclonal Antibody" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
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