Western Blot (WB)
(Western blot analysis of SRPX1 in SK-N-SH cell lysate with SRPX1 antibody at 0.25 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit SRPX1 Polyclonal Antibody | anti-SRPX antibody
SRPX1 Antibody
Gene Names
SRPX; DRS; ETX1; SRPX1; HEL-S-83p
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
SRPX1 Antibody is affinity chromatography purified via peptide column.
Synonyms
SRPX1; Polyclonal Antibody; SRPX1 Antibody; DRS; ETX1; HEL-S-83p; Sushi repeat-containing protein SRPX; sushi-repeat-containing protein; X-linked; anti-SRPX antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
SRPX1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
464
Applicable Applications for anti-SRPX antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
SRPX1 antibody can be used for detection of SRPX1 by Western blot at 0.25 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
SRPX1 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human SRPX1.
Buffer
SRPX1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SRPX1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of SRPX1 in SK-N-SH cell lysate with SRPX1 antibody at 0.25 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of SRPX1 in SK-N-SH cell lysate with SRPX1 antibody at 0.25 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SRPX1 in human brain tissue with SRPX1 antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SRPX1 in human brain tissue with SRPX1 antibody at 5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of SRPX1 in human brain tissue with SRPX1 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of SRPX1 in human brain tissue with SRPX1 antibody at 20 μg/mL.)
Related Product Information for anti-SRPX antibody
SRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,382 Da
NCBI Official Full Name
sushi repeat-containing protein SRPX isoform 1
NCBI Official Synonym Full Names
sushi-repeat containing protein, X-linked
NCBI Official Symbol
SRPX
NCBI Official Synonym Symbols
DRS; ETX1; SRPX1; HEL-S-83p
NCBI Protein Information
sushi repeat-containing protein SRPX; sushi-repeat-containing protein, X-linked; sushi-repeat-containing protein, X chromosome; epididymis secretory sperm binding protein Li 83p
UniProt Protein Name
Sushi repeat-containing protein SRPX
Protein Family
UniProt Gene Name
SRPX
UniProt Synonym Gene Names
ETX1
UniProt Entry Name
SRPX_HUMAN
Uniprot Description
SRPX: May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: Xp21.1
Cellular Component: cell surface; membrane; endoplasmic reticulum; autophagic vacuole
Biological Process: phagolysosome formation; autophagy; cell adhesion
Research Articles on SRPX
Similar Products
Product Notes
The SRPX srpx (Catalog #AAA151426) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRPX1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SRPX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). SRPX1 antibody can be used for detection of SRPX1 by Western blot at 0.25 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the SRPX srpx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRPX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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