Typical Testing Data/Standard Curve (for reference only)
Sheep FRS2 ELISA Kit | FRS2 elisa kit
Sheep FRS2 (Fibroblast Growth Factor Receptor Substrate 2) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to FRS2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for FRS2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain FRS2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of FRS2. You can calculate the concentration of FRS2 in the samples by comparing the OD of the samples to the standard curve.
NCBI and Uniprot Product Information
Uniprot Description
FRS2: an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: membrane; integral to plasma membrane; plasma membrane; intercellular junction; endosome
Molecular Function: protein binding; phosphatase activator activity; neurotrophin TRKA receptor binding; transmembrane receptor protein tyrosine kinase adaptor protein activity; insulin receptor binding; fibroblast growth factor receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; activation of MAPKK activity; nerve growth factor receptor signaling pathway; activation of MAPK activity; gastrulation with mouth forming second; regulation of epithelial cell proliferation; regulation of apoptosis; G-protein coupled receptor protein signaling pathway; determination of anterior/posterior axis, embryo; induction of an organ; neuroblast proliferation; forebrain development; insulin receptor signaling pathway; innate immune response; optic placode formation involved in camera-type eye; transmembrane receptor protein tyrosine phosphatase signaling pathway
Research Articles on FRS2
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Product Notes
The Sheep FRS2 frs2 (Catalog #AAA2502137) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2502137 ELISA Kit recognizes Sheep FRS2. It is sometimes possible for the material contained within the vial of "FRS2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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