Western Blot (WB)
(Western blot analysis of HeLa cell lysate using SRPX antibody.)
Rabbit SRPX Polyclonal Antibody | anti-SRPX antibody
SRPX Antibody
Gene Names
SRPX; DRS; ETX1; SRPX1; HEL-S-83p
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
SRPX; Polyclonal Antibody; SRPX Antibody; DRS; ETX1; SRPX1; anti-SRPX antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (varies by lot)
Sequence Length
464
Applicable Applications for anti-SRPX antibody
Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Recombinant protein of human SRPX
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10700 / sc-10701
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Western Blot (WB)
(Western blot analysis of HeLa cell lysate using SRPX antibody.)
Western Blot (WB)
(Western blot analysis of HeLa cell lysate using SRPX antibody.)
Related Product Information for anti-SRPX antibody
X-linked retinitis pigmentosa (XLRP) is a retinal degeneration disorder. The most common form of XLRP has been localized to the gene locus RP3 by linkage and deletion analysis. RP3 maps to chromosome Xp21. 1 between CYBB and OTC. The sushi-repeat-containing protein, x chromosome (SRPX) gene, also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,382 Da
NCBI Official Full Name
sushi repeat-containing protein SRPX isoform 1
NCBI Official Synonym Full Names
sushi-repeat containing protein, X-linked
NCBI Official Symbol
SRPX
NCBI Official Synonym Symbols
DRS; ETX1; SRPX1; HEL-S-83p
NCBI Protein Information
sushi repeat-containing protein SRPX; epididymis secretory sperm binding protein Li 83p; sushi-repeat-containing protein, X chromosome; sushi-repeat-containing protein, X-linked
UniProt Protein Name
Sushi repeat-containing protein SRPX
Protein Family
UniProt Gene Name
SRPX
UniProt Synonym Gene Names
ETX1
UniProt Entry Name
SRPX_HUMAN
Uniprot Description
SRPX: May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: Xp21.1
Cellular Component: cell surface; membrane; endoplasmic reticulum; autophagic vacuole
Biological Process: phagolysosome formation; autophagy; cell adhesion
Research Articles on SRPX
Similar Products
Product Notes
The SRPX srpx (Catalog #AAA2526578) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRPX Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SRPX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the SRPX srpx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRPX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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