Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045820 at dilution of 1:100)
Rabbit anti-Human SRGAP2C Polyclonal Antibody | anti-SRGAP2C antibody
SRGAP2C Antibody
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045820 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045820 at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7045820 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7045820 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2B locus. The encoded protein lacks the GTPase activating protein domain compared to proteins encoded by SLIT-ROBO Rho GTPase activating protein 2, and acts antagonistically to these proteins in cortical neuron development. [provided by RefSeq, Dec 2012]
Uniprot Description
SRGAP2C: Involved in dendritic spine maturation through interaction with and inhibition of SRGAP2. Reduces the rate of spine maturation and indirectly increases neuronal migration. Changes dendritic spine morphology and density and may have implications for cognition, learning and memory. Homodimer. Interacts with SRGAP2; formation of the heterodimer alters SRGAP2 function
Chromosomal Location of Human Ortholog: 1p11.2
Cellular Component: cytoplasm
Molecular Function: GTPase activator activity; protein heterodimerization activity; protein homodimerization activity; Rac GTPase binding
Biological Process: extension of a leading process involved in cell locomotion in cerebral cortex radial glia guided migration; negative regulation of cell migration; negative regulation of filopodium formation
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Product Notes
The SRGAP2C srgap2c (Catalog #AAA7045820) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRGAP2C Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SRGAP2C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the SRGAP2C srgap2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRGAP2C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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