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Immunofluorescence (IF) (Immunofluorescent analysis of MCF-7 cells using MBS1499488 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Rabbit anti-Human SPCS1 Polyclonal Antibody | anti-SPCS1 antibody

SPCS1 Antibody

Gene Names
SPCS1; SPC1; SPC12; HSPC033; YJR010C-A
Reactivity
Human
Applications
ELISA, Immunofluorescence
Purity
>95%, Protein G Purified
Synonyms
SPCS1; Polyclonal Antibody; SPCS1 Antibody; Signal peptidase complex subunit 1 (EC:3.4.-.-); SPC12; HSPC033; Microsomal signal peptidase 12 kDa subunit; SPase 12 kDa subunit; anti-SPCS1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
169
Applicable Applications for anti-SPCS1 antibody
ELISA (EIA), Immunofluorescence (IF)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Signal peptidase complex subunit 1 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-100168 / sc-100167
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunofluorescence (IF)

(Immunofluorescent analysis of MCF-7 cells using MBS1499488 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescence (IF) (Immunofluorescent analysis of MCF-7 cells using MBS1499488 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-SPCS1 antibody
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,805 Da
NCBI Official Full Name
signal peptidase complex subunit 1
NCBI Official Synonym Full Names
signal peptidase complex subunit 1
NCBI Official Symbol
SPCS1
NCBI Official Synonym Symbols
SPC1; SPC12; HSPC033; YJR010C-A
NCBI Protein Information
signal peptidase complex subunit 1
UniProt Protein Name
Signal peptidase complex subunit 1
Protein Family
UniProt Gene Name
SPCS1
UniProt Synonym Gene Names
SPC12; SPase 12 kDa subunit
UniProt Entry Name
SPCS1_HUMAN

Uniprot Description

SPCS1: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family.

Protein type: Protease; Amino Acid Metabolism - lysine degradation; Endoplasmic reticulum; Membrane protein, multi-pass; EC 3.4.-.-; Cofactor and Vitamin Metabolism - biotin; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; signal peptidase complex

Molecular Function: peptidase activity; protein binding

Biological Process: cellular protein metabolic process; gene expression; protein targeting to ER; proteolysis; regulation of insulin secretion; signal peptide processing; SRP-dependent cotranslational protein targeting to membrane; translation

Research Articles on SPCS1

Similar Products

Product Notes

The SPCS1 spcs1 (Catalog #AAA1499488) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPCS1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPCS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF). Researchers should empirically determine the suitability of the SPCS1 spcs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPCS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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