Immunohistochemistry (IHC)
(Anti-SPC18 / SEC11A antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit anti-Human SPC18 / SEC11A Polyclonal Antibody | anti-SPC18 antibody
Rabbit Polyclonal to Human SPC18 / SEC11A
Immunohistochemistry (IHC)
(Anti-SPC18 / SEC11A antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-SPC18 / SEC11A antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Western Blot (WB)
(SC11A Antibody (Center) Western blot of HepG2 cell line lysates (35 ug/lane). This demonstrates the SC11A antibody detected the SC11A protein (arrow).)
Western Blot (WB)
(SC11A Antibody (Center) Western blot of HepG2 cell line lysates (35 ug/lane). This demonstrates the SC11A antibody detected the SC11A protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Dec 2012]
Uniprot Description
SEC11A: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the peptidase S26B family.
Protein type: EC 3.4.21.89; Membrane protein, integral; Protease
Chromosomal Location of Human Ortholog: 15q25.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: serine-type peptidase activity
Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; signal peptide processing; gene expression; proteolysis; regulation of insulin secretion
Research Articles on SPC18
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Product Notes
The SPC18 sec11a (Catalog #AAA248259) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human SPC18 / SEC11A reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPC18 / SEC11A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (5 ug/ml), WB (1:1000). Researchers should empirically determine the suitability of the SPC18 sec11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPC18 / SEC11A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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