Immunohistochemistry (IHC)
(Anti-SPARCL1 antibody, MBS176168, IHC(P)IHC(P): Rat Brain Tissue )
Rabbit SPARCL1 Polyclonal Antibody | anti-SPARCL1 antibody
Anti-SPARCL1 antibody
Gene Names
SPARCL1; SC1; MAST9; PIG33; MAST 9
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen affinity purified.
Synonyms
SPARCL1; Polyclonal Antibody; Anti-SPARCL1 antibody; SPARC-like protein 1; SPARC-like 1(hevin); Ecm2 antibody; Extracellular matrix protein 2 antibody; Hevin antibody; High endothelial venule protein antibody; MAST 9 antibody; mast9 antibody; Matrix glycoprotein Sc1 antibody; PIG33 antibody; proliferation inducing protein 33 antibody; RAGS1 antigen antibody; SC1 antibody; SPARC like 1 antibody; SPARC-like protein 1 antibody; Sparcl1 antibody; SPRL1_HUMAN antibody; anti-SPARCL1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
664
Applicable Applications for anti-SPARCL1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human SPARCL1 (649-664aa HCFGIKEEDIDENLLF), identical to the related mouse and rat sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Immunohistochemistry (IHC)
(Anti-SPARCL1 antibody, MBS176168, IHC(P)IHC(P): Rat Brain Tissue )
Immunohistochemistry (IHC)
(Anti-SPARCL1 antibody, MBS176168, IHC(P)IHC(P): Rat Brain Tissue )
Western Blot (WB)
(Anti-SPARCL1 antibody, MBS176168, Western blottingLane 1: Rat Lung Tissue LysateLane 2: Mouse Lung Tissue LysateLane 3: PANC Cell LysateLane 4: A549 Cell LysateLane 5: COLO320 Cell LysateLane 6: MCF-7 Cell LysateLane 7: HT1080 Cell Lysate )
Western Blot (WB)
(Anti-SPARCL1 antibody, MBS176168, Western blottingLane 1: Rat Lung Tissue LysateLane 2: Mouse Lung Tissue LysateLane 3: PANC Cell LysateLane 4: A549 Cell LysateLane 5: COLO320 Cell LysateLane 6: MCF-7 Cell LysateLane 7: HT1080 Cell Lysate )
Immunohistochemistry (IHC)
(Anti-SPARCL1 antibody, MBS176168, IHC(P)IHC(P): Human Intestinal Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-SPARCL1 antibody, MBS176168, IHC(P)IHC(P): Human Intestinal Cancer Tissue )
Related Product Information for anti-SPARCL1 antibody
Description: Rabbit IgG polyclonal antibody for SPARC-like protein 1(SPARCL1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: SPARCL1(SPARC-Like Protein 1), also known as HEVIN, is a protein that in humans is encoded by the SPARCL1 gene. The cells in high endothelial venules(HEVs) in lymphoid tissues have a plump, almost cuboidal, appearance and support high levels of lymphocyte extravasation from blood, possibly due to the presence of desmosome-like junctions rather than tight junctions in the HEVs. In chronic inflammation, the activated endothelium of nonlymphoid tissues acquires an HEV-like morphology and function. Hevin is highly expressed in HEV and is though to contribute to the induction or maintenance of features of the HEV endothelium that facilitate lymphocyte migration(Girard and Springer, 1995).
Background: SPARCL1(SPARC-Like Protein 1), also known as HEVIN, is a protein that in humans is encoded by the SPARCL1 gene. The cells in high endothelial venules(HEVs) in lymphoid tissues have a plump, almost cuboidal, appearance and support high levels of lymphocyte extravasation from blood, possibly due to the presence of desmosome-like junctions rather than tight junctions in the HEVs. In chronic inflammation, the activated endothelium of nonlymphoid tissues acquires an HEV-like morphology and function. Hevin is highly expressed in HEV and is though to contribute to the induction or maintenance of features of the HEV endothelium that facilitate lymphocyte migration(Girard and Springer, 1995).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
61,760 Da
NCBI Official Full Name
SPARC-like protein 1
NCBI Official Synonym Full Names
SPARC-like 1 (hevin)
NCBI Official Symbol
SPARCL1
NCBI Official Synonym Symbols
SC1; MAST9; PIG33; MAST 9
NCBI Protein Information
SPARC-like protein 1; high endothelial venule protein; proliferation-inducing protein 33
UniProt Protein Name
SPARC-like protein 1
Protein Family
UniProt Gene Name
SPARCL1
UniProt Synonym Gene Names
Hevin
UniProt Entry Name
SPRL1_HUMAN
Uniprot Description
SPARCL1: Belongs to the SPARC family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 4q22.1
Cellular Component: extracellular space; proteinaceous extracellular matrix
Molecular Function: calcium ion binding
Biological Process: signal transduction
Research Articles on SPARCL1
Similar Products
Product Notes
The SPARCL1 sparcl1 (Catalog #AAA176168) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SPARCL1 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SPARCL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the SPARCL1 sparcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPARCL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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