Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using SOX4 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human SOX4 Polyclonal Antibody | anti-SOX4 antibody
SOX4 Antibody
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using SOX4 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using SOX4 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
NCBI and Uniprot Product Information
NCBI Description
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]
Uniprot Description
SOX4: Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 6p22.3
Cellular Component: cytoplasm; mitochondrion; nucleoplasm; nucleus
Molecular Function: protein binding; transcription factor activity
Biological Process: DNA damage response, detection of DNA damage; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; glial cell development; glial cell proliferation; glucose homeostasis; heart development; limb bud formation; negative regulation of cell proliferation; negative regulation of protein export from nucleus; negative regulation of protein ubiquitination; neural tube formation; positive regulation of apoptosis; positive regulation of cell proliferation; positive regulation of insulin secretion; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of translation; positive regulation of Wnt receptor signaling pathway; pro-B cell differentiation; protein stabilization; regulation of protein stability; regulation of transcription, DNA-dependent; skeletal development; spinal cord development; spinal cord motor neuron differentiation; sympathetic nervous system development; T cell differentiation; Wnt receptor signaling pathway through beta-catenin
Research Articles on SOX4
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Product Notes
The SOX4 sox4 (Catalog #AAA9417120) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SOX4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SOX4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the SOX4 sox4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOX4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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