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Goat SOX21 Polyclonal Antibody | anti-SOX21 antibody

Goat anti-SOX21 Antibody

Gene Names
SOX21; SOX25
Reactivity
Expected from sequence similarity: Human, Mouse, Rat
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
SOX21; Polyclonal Antibody; Goat anti-SOX21 Antibody; SRY (sex determining region Y)-box 21; SOX25; SRY-box 21; SOX25 antibody; SRY (sex determining region Y)-box 21 antibody; SRY-box 21 antibody; SOX21 antibody; anti-SOX21 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
GVADAEHPALKAG
Sequence Length
276
Applicable Applications for anti-SOX21 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Preliminary experiments gave an approx 38kDa band in Mouse Fetal Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 28.6kDa according to NP_009015.1. The 38kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence C-GVADAEHPALKAG, from the internal region of the protein sequence according to NP_009015.1.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,580 Da
NCBI Official Full Name
transcription factor SOX-21
NCBI Official Synonym Full Names
SRY-box 21
NCBI Official Symbol
SOX21
NCBI Official Synonym Symbols
SOX25
NCBI Protein Information
transcription factor SOX-21
UniProt Protein Name
Transcription factor SOX-21
Protein Family
UniProt Gene Name
SOX21
UniProt Synonym Gene Names
SOX25; SOXA
UniProt Entry Name
SOX21_HUMAN

NCBI Description

SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]

Uniprot Description

SOX21: May play a role as an activator of transcription of OPRM1.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 13q32.1

Cellular Component: nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: hair follicle development; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; stem cell differentiation; transcription, DNA-dependent

Research Articles on SOX21

Similar Products

Product Notes

The SOX21 sox21 (Catalog #AAA422354) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-SOX21 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SOX21 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Preliminary experiments gave an approx 38kDa band in Mouse Fetal Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 28.6kDa according to NP_009015.1. The 38kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the SOX21 sox21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: GVADAEHPAL KAG. It is sometimes possible for the material contained within the vial of "SOX21, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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