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Western Blot (WB) (Western Blot: Sample: Recombinant SNX13, Human.)

Rabbit anti-Human Sorting Nexin 13 Polyclonal Antibody | anti-SNX13 antibody

Polyclonal Antibody to Sorting Nexin 13 (SNX13)

Gene Names
SNX13; RGS-PX1
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Sorting Nexin 13; Polyclonal Antibody; Polyclonal Antibody to Sorting Nexin 13 (SNX13); anti-SNX13 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against SNX13. It has beenselected for its ability to recognize SNX13 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
500ug/mL (varies by lot)
Sequence Length
958
Applicable Applications for anti-SNX13 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Fragment
SNX13 (Ala97~Asn284)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant SNX13 (Ala97~Asn284) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2063926
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Recombinant SNX13, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant SNX13, Human.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Pancreas Tissue)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Pancreas Tissue)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Lung Cancer Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Lung Cancer Tissue.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Stomach Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Stomach Tissue.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Glioma Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Glioma Tissue.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
110,960 Da
NCBI Official Full Name
sorting nexin-13 isoform b
NCBI Official Synonym Full Names
sorting nexin 13
NCBI Official Symbol
SNX13
NCBI Official Synonym Symbols
RGS-PX1
NCBI Protein Information
sorting nexin-13
UniProt Protein Name
Sorting nexin-13
Protein Family
UniProt Gene Name
SNX13
UniProt Synonym Gene Names
KIAA0713

NCBI Description

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]

Uniprot Description

SNX13: May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis. Acts as a GAP for Galphas. Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: early endosome; early endosome membrane

Molecular Function: phosphatidylinositol 3-phosphate binding; phosphatidylinositol binding

Biological Process: intracellular protein transport; negative regulation of signal transduction; positive regulation of GTPase activity

Research Articles on SNX13

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Product Notes

The SNX13 snx13 (Catalog #AAA2028463) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Sorting Nexin 13 (SNX13) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Sorting Nexin 13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the SNX13 snx13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sorting Nexin 13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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