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Western Blot (WB) (Western blot analysis of SNX27 Antibody (Center) in 293 cell line lysates (35ug/lane). SNX27 (arrow) was detected using the purified Pab.)

Rabbit SNX27 Polyclonal Antibody | anti-SNX27 antibody

SNX27 Antibody (Center)

Gene Names
SNX27; MRT1; MY014
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SNX27; Polyclonal Antibody; SNX27 Antibody (Center); Sorting nexin-27; KIAA0488; anti-SNX27 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SNX27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human SNX27.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
313-340
Sequence Length
528
Applicable Applications for anti-SNX27 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of SNX27 Antibody (Center) in 293 cell line lysates (35ug/lane). SNX27 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of SNX27 Antibody (Center) in 293 cell line lysates (35ug/lane). SNX27 (arrow) was detected using the purified Pab.)
Related Product Information for anti-SNX27 antibody
SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.
Product Categories/Family for anti-SNX27 antibody
References
Lunn, M.L., et al. Nat. Neurosci. 10(10):1249-1259(2007)
Nassirpour, R., et al. Channels (Austin) 1(5):331-333(2007)
MacNeil, A.J., et al. Biochem. Biophys. Res. Commun. 359(4):848-853(2007)
Rincon, E., et al. Mol. Cell Proteomics 6(6):1073-1087(2007)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
61265
NCBI Official Full Name
sorting nexin-27
NCBI Official Synonym Full Names
sorting nexin family member 27
NCBI Official Symbol
SNX27
NCBI Official Synonym Symbols
MRT1; MY014
NCBI Protein Information
sorting nexin-27
UniProt Protein Name
Sorting nexin-27
Protein Family
UniProt Gene Name
SNX27
UniProt Synonym Gene Names
KIAA0488
UniProt Entry Name
SNX27_HUMAN

NCBI Description

This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. [provided by RefSeq, Jul 2008]

Uniprot Description

SNX27: Involved in endocytic trafficking. In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes. Belongs to the sorting nexin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleoplasm; retromer complex; early endosome membrane; early endosome; cytoplasm; immunological synapse; cytosol

Molecular Function: protein binding; phosphatidylinositol 3-phosphate binding

Biological Process: intracellular protein transport; establishment of natural killer cell polarity; endosome to lysosome transport; signal transduction; endosome transport

Research Articles on SNX27

Similar Products

Product Notes

The SNX27 snx27 (Catalog #AAA9206961) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 313-340. The SNX27 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's SNX27 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SNX27 snx27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNX27, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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