Rabbit SNAP29 Polyclonal Antibody | anti-SNAP29 antibody

SNAP29 Polyclonal Antibody

Cat. Num. AAA2527975

• Gene Names: SNAP29; CEDNIK; SNAP-29
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: SNAP29; Polyclonal Antibody; SNAP29 Polyclonal Antibody; CEDNIK; SNAP-29; anti-SNAP29 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 2.5mg/mL (varies by lot)
• Sequence Length: 258

• Applicable Applications for anti-SNAP29 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:30-1:150
• Immunogen: Recombinant protein of human SNAP29
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using SNAP29 Polyclonal Antibody at dilution 1:45)

Related Product Information for anti-SNAP29 antibody

This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 4759154
• NCBI GeneID: 9342
• NCBI Accession #: NP_004773.1
• NCBI GenBank Nucleotide #: NM_004782.3
• Molecular Weight: 28,970 Da
• NCBI Official Full Name: synaptosomal-associated protein 29
• NCBI Official Synonym Full Names: synaptosomal-associated protein, 29kDa
• NCBI Official Symbol: SNAP29
• NCBI Official Synonym Symbols: CEDNIK; SNAP-29
• NCBI Protein Information: synaptosomal-associated protein 29; soluble 29 kDa NSF attachment protein; synaptosomal-associated protein, 29kD; vesicle-membrane fusion protein SNAP-29
• UniProt Protein Name: Synaptosomal-associated protein 29
• Protein Family: SNAP25 homologous protein
• UniProt Gene Name: SNAP29
• UniProt Synonym Gene Names: SNAP-29
• UniProt Entry Name: SNP29_HUMAN

NCBI Description

This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

SNAP29: Involved in multiple membrane trafficking steps. Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK). CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. Belongs to the SNAP-25 family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: SNARE complex; centrosome; neuron projection; cytoplasm; plasma membrane; synapse; cell junction

Molecular Function: SNAP receptor activity; syntaxin binding

Biological Process: synaptic vesicle fusion to presynaptic membrane; protein transport; exocytosis; autophagic vacuole fusion; vesicle targeting; synaptic vesicle priming

Disease: Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome