Western Blot (WB)
(Western blot analysis of SMAD7 expression in HeLa (A); A431 (B); SP2/0 (C); PC12 (D) whole cell lysates.)
Rabbit SMAD7 Polyclonal Antibody | anti-SMAD7 antibody
SMAD7 Antibody
Gene Names
SMAD7; CRCS3; MADH7; MADH8
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
SMAD7; Polyclonal Antibody; SMAD7 Antibody; Purified Polyclonal SMAD7 Antibody; Polyclonal SMAD7 antibody; Anti-SMAD7 antibody; MADH7 antibody; MADH8 antibody; Mothers against decapentaplegic homolog 7 antibody; MAD homolog 7 antibody; Mothers against DPP homolog 7 antibody; Mothers against decapentaplegic homolog 8 antibody; MAD homolog 8 antibody; Mothers against DPP homolog 8 antibody; SMAD family member 7 antibody; SMAD 7 antibody; Smad7 antibody; hSMAD7 antibody; anti-SMAD7 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of SMAD7 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
426
Applicable Applications for anti-SMAD7 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
SMAD7 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SMAD7 as the immunogen
Cross-Reactivity
Mouse, Rat, Pig
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of SMAD7 expression in HeLa (A); A431 (B); SP2/0 (C); PC12 (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of SMAD7 expression in HeLa (A); A431 (B); SP2/0 (C); PC12 (D) whole cell lysates.)
Related Product Information for anti-SMAD7 antibody
SMAD7 is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access.
Product Categories/Family for anti-SMAD7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Smad7
NCBI Official Synonym Full Names
SMAD family member 7
NCBI Official Symbol
SMAD7
NCBI Official Synonym Symbols
CRCS3; MADH7; MADH8
NCBI Protein Information
mothers against decapentaplegic homolog 7
Protein Family
NCBI Description
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Research Articles on SMAD7
Similar Products
Product Notes
The SMAD7 (Catalog #AAA5314651) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SMAD7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the SMAD7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMAD7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
