Western Blot (WB)
(Western Blot analysis of various cells using SLK Polyclonal Antibody at dilution of 1:1000.)
Rabbit SLK Polyclonal Antibody | anti-SLK antibody
SLK Polyclonal Antibody
Western Blot (WB)
(Western Blot analysis of various cells using SLK Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of various cells using SLK Polyclonal Antibody at dilution of 1:1000.)
NCBI and Uniprot Product Information
Observed MW: 150
Uniprot Description
SLK: a microtubule-associated protein kinase required for progression through G2. Co-localizes with the mitotic spindle in cells undergoing mitosis. Regulates actin reorganization during cell adhesion and spreading via a Rac1-mediated pathway. Signals via ASK1 and p38 to promote apoptosis. Activated in response to anoxia and ischemia-reperfusion injury in cell culture. It inhibits the protective aspects of the endoplasmic reticulum stress response, thus contributing to its proapoptotic effect. Two alternatively-spliced isoforms have been described.
Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; SLK subfamily
Chromosomal Location of Human Ortholog: 10q24.33
Cellular Component: cytoplasm
Molecular Function: ATP binding; identical protein binding; protein homodimerization activity; protein serine/threonine kinase activity
Biological Process: activation of protein kinase activity; apoptosis; protein amino acid autophosphorylation; regulation of apoptosis; regulation of mitotic cell cycle; stress-activated protein kinase signaling pathway
Research Articles on SLK
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Product Notes
The SLK slk (Catalog #AAA2537867) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLK Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-1:100, ELISA: 1:5000-1:20000. Researchers should empirically determine the suitability of the SLK slk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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