Rabbit SLC52A1 Polyclonal Antibody | anti-SLC52A1 antibody

SLC52A1 Polyclonal Antibody

Cat. Num. AAA2524717

• Gene Names: SLC52A1; PAR2; RFT1; RBFVD; RFVT1; hRFT1; GPCR42; GPR172B
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: SLC52A1; Polyclonal Antibody; SLC52A1 Polyclonal Antibody; PAR2; RFT1; RBFVD; RFVT1; hRFT1; GPCR42; GPR172B; anti-SLC52A1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 2.8mg/mL (varies by lot)
• Sequence Length: 448

• Applicable Applications for anti-SLC52A1 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:50-1:200
• Immunogen: Synthetic peptide of human SLC52A1
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using SLC52A1 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using SLC52A1 Polyclonal Antibody at dilution 1:40)

Related Product Information for anti-SLC52A1 antibody

Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficiency of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.

NCBI and Uniprot Product Information

• NCBI GI #: 157388953
• NCBI GeneID: 55065
• NCBI Accession #: NP_060456.3
• NCBI GenBank Nucleotide #: NM_017986.3
• Molecular Weight: 16,360 Da
• NCBI Official Full Name: solute carrier family 52, riboflavin transporter, member 1
• NCBI Official Synonym Full Names: solute carrier family 52 (riboflavin transporter), member 1
• NCBI Official Symbol: SLC52A1
• NCBI Official Synonym Symbols: PAR2; RFT1; RBFVD; RFVT1; hRFT1; GPCR42; GPR172B
• NCBI Protein Information: solute carrier family 52, riboflavin transporter, member 1; G protein-coupled receptor 172B; G-protein coupled receptor GPCR42; PERV-A receptor 2; porcine endogenous retrovirus A receptor 2
• UniProt Protein Name: Solute carrier family 52, riboflavin transporter, member 1
• Protein Family: Solute carrier family
• UniProt Gene Name: SLC52A1
• UniProt Synonym Gene Names: GPR172B; PAR2; RFT1; PERV-A receptor 2; hRFT1
• UniProt Entry Name: S52A1_HUMAN

NCBI Description

Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficiency of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013]

Uniprot Description

GPR172B: Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A). Haploinsufficiency in SLC52A1 can cause maternal riboflavin deficiency. In the newborn infant, this can lead to a transient riboflavin-responsive disorder with clinical and biochemical features of multiple acyl-CoA dehydrogenase deficiency. Belongs to the riboflavin transporter family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: integral to plasma membrane

Molecular Function: viral receptor activity; riboflavin transporter activity

Biological Process: entry of virus into host cell; riboflavin transport

Disease: Riboflavin Deficiency