Western Blot (WB)
(Western Blot analysis of GPR172B expression in transfected 293T cell line by GPR172B polyclonal antibody. Lane 1: GPR172B transfected lysate (49.28kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human SLC52A1 Polyclonal Antibody | anti-SLC52A1 antibody
SLC52A1 (Solute Carrier Family 52, Riboflavin Transporter, Member 1, Porcine Endogenous Retrovirus A Receptor 2, PERV-A Receptor 2, Protein GPR172B, Riboflavin Transporter 1, hRFT1, GPR172B, PAR2, RFT1)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of GPR172B expression in transfected 293T cell line by GPR172B polyclonal antibody. Lane 1: GPR172B transfected lysate (49.28kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of GPR172B expression in transfected 293T cell line by GPR172B polyclonal antibody. Lane 1: GPR172B transfected lysate (49.28kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficiency of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013]
Uniprot Description
GPR172B: Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A). Haploinsufficiency in SLC52A1 can cause maternal riboflavin deficiency. In the newborn infant, this can lead to a transient riboflavin-responsive disorder with clinical and biochemical features of multiple acyl-CoA dehydrogenase deficiency. Belongs to the riboflavin transporter family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: integral to plasma membrane
Molecular Function: viral receptor activity; riboflavin transporter activity
Biological Process: entry of virus into host cell; riboflavin transport
Disease: Riboflavin Deficiency
Research Articles on SLC52A1
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Product Notes
The SLC52A1 slc52a1 (Catalog #AAA6003419) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SLC52A1 (Solute Carrier Family 52, Riboflavin Transporter, Member 1, Porcine Endogenous Retrovirus A Receptor 2, PERV-A Receptor 2, Protein GPR172B, Riboflavin Transporter 1, hRFT1, GPR172B, PAR2, RFT1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC52A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the SLC52A1 slc52a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MAAPTLGRLV LTHLLVALFG MGSWAAVNGI WVELPVVVKD LPEGWSLPSY LSVVVALGNL GLLVVTLWRR LAPGKGEQVP IQVVQVLSVV GTALLAPLWH HVAPVAGQLH SVAFLTLALV LAMACCTSNV TFLPFLSHLP PPFLRSFFLG QGLSALLPCV LALVQGVGRL ECPPAPTNGT SGPPLDFPER FPASTFFWAL TALLVTSAAA FRGLLLLLPS LPSVTTGGSG PELQLGSPGA EEEEKEEEEA LPLQEPPSQA AGTIPGPDPE VHQLFSAHGA FLLGLMAFTS AVTNGVLPSV QSFSCLPYGR LAYHLAVVLG SAANPLACFL AMGVLCRSLA GLVGLSLLGM LFGAYLMALA ILSPCPPLVG TTAGVVLVVL SWVLCLCVFS YVKVAASSLL HGGGRPALLA AGVAIQVGSL LGAGAMFPPT SIYHVFQSRK DCVDPCGP. It is sometimes possible for the material contained within the vial of "SLC52A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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