Western Blot (WB)
(SLC4A5 antibody (MBS5301822) used at 1 ug/ml to detect target protein.)
Rabbit SLC4A5 Polyclonal Antibody | anti-SLC4A5 antibody
SLC4A5 antibody
Western Blot (WB)
(SLC4A5 antibody (MBS5301822) used at 1 ug/ml to detect target protein.)
Western Blot (WB)
(SLC4A5 antibody (MBS5301822) used at 1 ug/ml to detect target protein.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC4A5: Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry of 2:1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na(+):HCO3(-) cotransport in hepatocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH. Belongs to the anion exchanger (TC 2.A.31) family. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family
Chromosomal Location of Human Ortholog: 2p13
Cellular Component: integral to plasma membrane; apical plasma membrane; plasma membrane; integral to membrane
Molecular Function: inorganic anion exchanger activity; sodium:bicarbonate symporter activity
Biological Process: renal system process; cerebrospinal fluid secretion; regulation of gene expression; bicarbonate transport; retina development in camera-type eye; regulation of intracellular pH; regulation of systemic arterial blood pressure; epithelial cell development; ion transport; transmembrane transport; mitochondrion distribution
Research Articles on SLC4A5
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Product Notes
The SLC4A5 slc4a5 (Catalog #AAA5301822) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SLC4A5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1 ug/ml. Researchers should empirically determine the suitability of the SLC4A5 slc4a5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC4A5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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