Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) ((0.1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Goat SLC47A2 Polyclonal Antibody | anti-SLC47A2 antibody

Goat anti-SLC47A2 Antibody

Gene Names
SLC47A2; MATE2; MATE2K; MATE2-B; MATE2-K
Reactivity
Tested: Human; Expected from sequence similarity: Human
Applications
ELISA, Western Blot
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
SLC47A2; Polyclonal Antibody; Goat anti-SLC47A2 Antibody; Goat Anti-SLC47A2 Antibody; solute carrier family 47; member 2; FLJ31196; MATE2; MATE2-B; MATE2-K; MATE2K; H+/organic cation antiporter; MATE-2; OTTHUMP00000065791; hMATE-2; kidney-specific H(+)/organic cation antiporter; multidrug and toxin extrusion 2; multidrug and toxin; SLC47A2 antibody; member 2 antibody; FLJ31196 antibody; MATE2 antibody; MATE2-B antibody; MATE2-K antibody; MATE2K antibody; H+/organic cation antiporter antibody; MATE-2 antibody; hMATE-2 antibody; kidney-specific H(+)/organic cation antiporter antibody; multidrug and toxin extrusion 2 antibody; multidrug and toxin antibody; anti-SLC47A2 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Tested: Human; Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
QRAESTATRPGPEK
Sequence Length
602
Applicable Applications for anti-SLC47A2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 60kDa band observed in Human Testis lysates (calculated MW of 61. 0kDa according to NP_001093116.1). Recommended concentration: 0.1-0.3ug/ml.
Immunogen
Peptide with sequence C-QRAESTATRPGPEK, from the internal region (near C terminus) of the protein sequence according to NP_690872.2; NP_001093116.1.
Epitope
Internal region (near C Terminus)
Note
This antibody is expected to recognize both reported isoforms (NP_690872.2; NP_001093116.1).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

Western Blot (WB)

((0.1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Western Blot (WB) ((0.1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,344 Da
NCBI Official Full Name
multidrug and toxin extrusion protein 2 isoform 1
NCBI Official Synonym Full Names
solute carrier family 47 member 2
NCBI Official Symbol
SLC47A2
NCBI Official Synonym Symbols
MATE2; MATE2K; MATE2-B; MATE2-K
NCBI Protein Information
multidrug and toxin extrusion protein 2
UniProt Protein Name
Multidrug and toxin extrusion protein 2
UniProt Gene Name
SLC47A2
UniProt Synonym Gene Names
MATE2; MATE-2; hMATE-2
UniProt Entry Name
S47A2_HUMAN

NCBI Description

This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

SLC47A2: Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter; Transporter, SLC family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: drug transporter activity; drug:hydrogen antiporter activity

Biological Process: drug export; multidrug transport; transmembrane transport

Research Articles on SLC47A2

Similar Products

Product Notes

The SLC47A2 slc47a2 (Catalog #AAA422632) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-SLC47A2 Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC47A2 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 60kDa band observed in Human Testis lysates (calculated MW of 61. 0kDa according to NP_001093116.1). Recommended concentration: 0.1-0.3ug/ml. Researchers should empirically determine the suitability of the SLC47A2 slc47a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QRAESTATRP GPEK. It is sometimes possible for the material contained within the vial of "SLC47A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.