Western Blot (WB)
(S47A2 Antibody (N-term) western blot analysis in mouse kidney tissue and A2058 cell line lysates (35ug/lane).This demonstrates the S47A2 antibody detected the S47A2 protein (arrow).)
Rabbit anti-Human, mouse S47A2 Polyclonal Antibody | anti-SLC47A2 antibody
S47A2 Antibody (N-term)
Western Blot (WB)
(S47A2 Antibody (N-term) western blot analysis in mouse kidney tissue and A2058 cell line lysates (35ug/lane).This demonstrates the S47A2 antibody detected the S47A2 protein (arrow).)
Western Blot (WB)
(S47A2 Antibody (N-term) western blot analysis in mouse kidney tissue and A2058 cell line lysates (35ug/lane).This demonstrates the S47A2 antibody detected the S47A2 protein (arrow).)
Kajiwara, M., et al. J. Hum. Genet. 54(1):40-46(2009)
Ohta, K.Y., et al. J Pharm Pharm Sci 12(3):388-396(2009)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC47A2: Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: integral to membrane; plasma membrane
Molecular Function: drug transporter activity; antiporter activity
Biological Process: multidrug transport; transmembrane transport
Research Articles on SLC47A2
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Product Notes
The SLC47A2 slc47a2 (Catalog #AAA9206268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 125-153. The S47A2 Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's S47A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SLC47A2 slc47a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S47A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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