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Rabbit anti-Human SLC39A5 Polyclonal Antibody | anti-SLC39A5 antibody

SLC39A5 Antibody

Gene Names
SLC39A5; ZIP5; MYP24; LZT-Hs7
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
SLC39A5; Polyclonal Antibody; SLC39A5 Antibody; LZT Hs7; MGC34778; OTTHUMP00000211153; OTTHUMP00000211154; S39A5_HUMAN; solute carrier family 39 (metal ion transporter); member 5; Solute carrier family 39 member 5; Zinc transporter ZIP5 [Precursor]; Zinc transporter ZIP5; ZIP 5; ZIP-5; ZIP5; Zrt and Irt like protein 5; Zrt- and Irt-like protein 5; anti-SLC39A5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SLC39A5 Antibody detects endogenous levels of SLC39A5.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SLC39A5 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human SLC39A5.
Conjugation
Unconjugated
Similarity
Belongs to the ZIP transporter (TC 2. A. 5) family.
Post Translational Modifications
Glycosylated.
Tissue Specificity
Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
Function
May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Seems to play a central role in controlling organismal zinc status (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-SLC39A5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56,461 Da
NCBI Official Full Name
zinc transporter ZIP5
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 5
NCBI Official Symbol
SLC39A5
NCBI Official Synonym Symbols
ZIP5; MYP24; LZT-Hs7
NCBI Protein Information
zinc transporter ZIP5; zrt- and Irt-like protein 5; solute carrier family 39 member 5; solute carrier family 39 (metal ion transporter), member 5
UniProt Protein Name
Zinc transporter ZIP5
Protein Family
UniProt Gene Name
SLC39A5
UniProt Synonym Gene Names
ZIP5; ZIP-5
UniProt Entry Name
S39A5_HUMAN

NCBI Description

The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

Uniprot Description

SLC39A5: May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status. Belongs to the ZIP transporter (TC 2.A.5) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: basolateral plasma membrane; integral to membrane

Molecular Function: metal ion transmembrane transporter activity

Biological Process: positive regulation of nuclear mRNA splicing, via spliceosome; BMP signaling pathway; eye development; zinc ion transport; transmembrane transport

Disease: Myopia 24, Autosomal Dominant

Research Articles on SLC39A5

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Product Notes

The SLC39A5 slc39a5 (Catalog #AAA9630242) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC39A5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC39A5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the SLC39A5 slc39a5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC39A5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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