Rabbit anti-Human SLC39A14 Polyclonal Antibody | anti-SLC39A14 antibody
SLC39A14 (KIAA0062, ZIP14, Zinc transporter ZIP14, Solute carrier family 39 member 14)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: Immunohistochemistry (Paraffin): 5-7.5ug/ml
Immunohistochemistry (IHC)
(SLC39A14 was used in IHC to stain formalin-fixed, paraffin-embedded human prostate, followed by biotinylated goat, rabbit IgG, alkaline phosphatase-streptavidin and chromogen.)
Immunohistochemistry (IHC)
(SLC39A14 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney, followed by biotinylated goat, rabbit IgG, alkaline phosphatase-streptavidin and chromogen.)
NCBI and Uniprot Product Information
NCBI Description
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
Uniprot Description
Function: May mediate cellular uptake of nontransferrin-bound iron
By similarity. Broad-scope metal ion transporter with a preference for zinc uptake. Ref.7
Subunit structure: Homotrimer. Ref.6
Subcellular location: Cell membrane; Multi-pass membrane protein
Potential. Cell projection › lamellipodium. Note: Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae. Ref.6 Ref.7
Tissue specificity: Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes. Ref.1 Ref.7
Sequence similarities: Belongs to the ZIP transporter (TC 2.A.5) family. [View classification]
Sequence caution: The sequence BAA06685.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
Research Articles on SLC39A14
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Product Notes
The SLC39A14 slc39a14 (Catalog #AAA645600) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC39A14 (KIAA0062, ZIP14, Zinc transporter ZIP14, Solute carrier family 39 member 14) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC39A14 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry,. Dilution: Immunohistochemistry (Paraffin): 5-7.5ug/ml. Researchers should empirically determine the suitability of the SLC39A14 slc39a14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC39A14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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