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Western Blot (WB) (Western BlotPositive WB detected in: Mouse brain tissueAll lanes: SLC30A10 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 53,27,25 KDaObserved band size: 53 KDa)

Rabbit anti-Human, Mouse SLC30A10 Polyclonal Antibody | anti-SLC30A10 antibody

SLC30A10 Antibody

Gene Names
SLC30A10; ZNT8; ZRC1; HMDPC; ZNT10; ZnT-10; HMNDYT1
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
SLC30A10; Polyclonal Antibody; SLC30A10 Antibody; Zinc transporter 10 (ZnT-10) (Manganese transporter SLC30A10) (Solute carrier family 30 member 10); ZNT10 ZNT8; anti-SLC30A10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Applicable Applications for anti-SLC30A10 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
Recommended dilution:

WB: 1:500-1:5000
IHC: 1:100-1:500
IF: 1:50-1:500
Immunogen
Recombinant Human Zinc transporter 10 protein (58-278AA)
Conjugate
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Species
Homo sapiens (Human)
Research Area
Signal Transduction
Target Names
SLC30A10
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160941 / sc-160942
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze

Western Blot (WB)

(Western BlotPositive WB detected in: Mouse brain tissueAll lanes: SLC30A10 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 53,27,25 KDaObserved band size: 53 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: Mouse brain tissueAll lanes: SLC30A10 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 53,27,25 KDaObserved band size: 53 KDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human spleen tissue using MBS7044073 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human spleen tissue using MBS7044073 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of HepG-2 cells using MBS7044073 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of HepG-2 cells using MBS7044073 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-SLC30A10 antibody
Plays a pivotal role in manganese transport. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
zinc transporter 10
NCBI Official Synonym Full Names
solute carrier family 30 member 10
NCBI Official Symbol
SLC30A10
NCBI Official Synonym Symbols
ZNT8; ZRC1; HMDPC; ZNT10; ZnT-10; HMNDYT1
NCBI Protein Information
zinc transporter 10
UniProt Protein Name
Zinc transporter 10
Protein Family
UniProt Gene Name
SLC30A10
UniProt Synonym Gene Names
ZNT10; ZNT8; ZnT-10
UniProt Entry Name
ZNT10_HUMAN

NCBI Description

This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]

Uniprot Description

SLC30A10: May be involved in zinc transport out of the cell, being a zinc-efflux transporter. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: plasma membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: manganese ion transport; response to zinc ion

Disease: Hypermanganesemia With Dystonia, Polycythemia, And Cirrhosis

Research Articles on SLC30A10

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Product Notes

The SLC30A10 slc30a10 (Catalog #AAA7044073) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC30A10 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLC30A10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Recommended dilution: WB: 1:500-1:5000 IHC: 1:100-1:500 IF: 1:50-1:500. Researchers should empirically determine the suitability of the SLC30A10 slc30a10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC30A10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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