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Western Blot (WB) (Western BlotPositive WB detected in: 293 whole cell lysate, SH-SY5Y whole cell lysate, U87 whole cell lysateAll lanes: SLC11A2 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 63, 62, 65, 66 KDaObserved band size: 63 KDa)

Rabbit anti-Human SLC11A2 Polyclonal Antibody | anti-SLC11A2 antibody

SLC11A2 Antibody

Gene Names
SLC11A2; DCT1; DMT1; AHMIO1; NRAMP2
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>95%, Protein G purified
Synonyms
SLC11A2; Polyclonal Antibody; SLC11A2 Antibody; Natural resistance-associated macrophage protein 2; NRAMP 2; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; Solute carrier family 11 member 2; DCT1; DMT1; NRAMP2; ORF Names:OK/SW-cl.20; anti-SLC11A2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
561
Applicable Applications for anti-SLC11A2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:5000
IHC: 1:20-1:200
Immunogen
Recombinant Human Natural resistance-associated macrophage protein 2 protein (1-69AA)
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: 293 whole cell lysate, SH-SY5Y whole cell lysate, U87 whole cell lysateAll lanes: SLC11A2 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 63, 62, 65, 66 KDaObserved band size: 63 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: 293 whole cell lysate, SH-SY5Y whole cell lysate, U87 whole cell lysateAll lanes: SLC11A2 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 63, 62, 65, 66 KDaObserved band size: 63 KDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7105109 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7105109 at dilution of 1:100)
Related Product Information for anti-SLC11A2 antibody
Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
Product Categories/Family for anti-SLC11A2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
61,048 Da
NCBI Official Full Name
natural resistance-associated macrophage protein 2 isoform 3
NCBI Official Synonym Full Names
solute carrier family 11 member 2
NCBI Official Symbol
SLC11A2
NCBI Official Synonym Symbols
DCT1; DMT1; AHMIO1; NRAMP2
NCBI Protein Information
natural resistance-associated macrophage protein 2
UniProt Protein Name
Natural resistance-associated macrophage protein 2
UniProt Gene Name
SLC11A2
UniProt Synonym Gene Names
DCT1; DMT1; NRAMP2; NRAMP 2; DMT-1

NCBI Description

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]

Uniprot Description

Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.

Research Articles on SLC11A2

Similar Products

Product Notes

The SLC11A2 slc11a2 (Catalog #AAA7105109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC11A2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC11A2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:5000 IHC: 1:20-1:200. Researchers should empirically determine the suitability of the SLC11A2 slc11a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC11A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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