Western Blot (WB)
(FUSSEL18 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FUSSEL18 antibody detected the FUSSEL18 protein (arrow).)
Rabbit anti-Human FUSSEL18 Polyclonal Antibody | anti-SKOR2 antibody
FUSSEL18 Antibody (C-term)
Gene Names
SKOR2; CORL2; CH18515; FUSSEL18
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
FUSSEL18; Polyclonal Antibody; FUSSEL18 Antibody (C-term); SKI family transcriptional corepressor 2; Functional Smad-suppressing element on chromosome 18; Fussel-18; LBX1 corepressor 1-like protein; Ladybird homeobox corepressor 1-like protein; SKOR2; CORL2; anti-SKOR2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This FUSSEL18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 870-898 amino acids from the C-terminal region of human FUSSEL18.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.38 (varies by lot)
Sequence Positions
870-898
Sequence Length
296
Applicable Applications for anti-SKOR2 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(FUSSEL18 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FUSSEL18 antibody detected the FUSSEL18 protein (arrow).)
Western Blot (WB)
(FUSSEL18 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FUSSEL18 antibody detected the FUSSEL18 protein (arrow).)
Immunohistochemistry (IHC)
(FUSSEL18 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FUSSEL18 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(FUSSEL18 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FUSSEL18 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-SKOR2 antibody
SKOR2 exhibits transcriptional repressor activity (By similarity) and acts as a TGF-beta antagonist in the nervous system.
Product Categories/Family for anti-SKOR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
104235
NCBI Official Full Name
SKI family transcriptional corepressor 2 isoform 2
NCBI Official Synonym Full Names
SKI family transcriptional corepressor 2
NCBI Official Symbol
SKOR2
NCBI Official Synonym Symbols
CORL2; CH18515; FUSSEL18
NCBI Protein Information
SKI family transcriptional corepressor 2
UniProt Protein Name
SKI family transcriptional corepressor 2
Protein Family
UniProt Gene Name
SKOR2
UniProt Synonym Gene Names
CORL2; FUSSEL18; Fussel-18
UniProt Entry Name
SKOR2_HUMAN
Uniprot Description
FUSSEL18: Exhibits transcriptional repressor activity. Acts as a TGF-beta antagonist in the nervous system. Belongs to the SKI family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 18q21.1
Cellular Component: cytoplasm; nucleus
Molecular Function: SMAD binding; transcription corepressor activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway
Research Articles on SKOR2
1. Experiments performed using mice, but the observations maybe relevant to other organisms as well.
Similar Products
Product Notes
The SKOR2 skor2 (Catalog #AAA9215269) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 870-898. The FUSSEL18 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FUSSEL18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the SKOR2 skor2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FUSSEL18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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