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Western Blot (WB) (Western Blot: Sample: Lane1: Rat Serum; Lane2: Mouse Lung Tissue.)

Rabbit anti-Rat Signal Transducer And Activator Of Transcription 2 Polyclonal Antibody | anti-STAT2 antibody

Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2)

Reactivity
Rat
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Signal Transducer And Activator Of Transcription 2; Polyclonal Antibody; Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2); anti-STAT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against STAT2. It has beenselected for its ability to recognize STAT2 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
500ug/mL (varies by lot)
Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- RRLL KKMVSGTFLL RFSETSEGGI TCSWVEHQDD DKVLIYSVQP YTKEVLQSLP LTEIIRHYQV LAEENAPENP LRFLYPRVPR DEAFGCYYQE KVNLEERRKY LKHRLIVISN RQADELQQPL ELKQDPESLE LDAELMSVME LARDLELQSM LQVGLDLGVE PKPDPTLSPA PQILLEPDPA RALNQLLPEP DLPQDLQQLN TGEMEIFRNN INIDDVMPYG DPVLAGQSII EEAYRSCPSH FDVDGPLI
Sequence Length
857
Applicable Applications for anti-STAT2 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Fragment
STAT2 (Arg587~Ile838)
Organism Species
Rattus norvegicus (Rat)
Cross Reactivity
Mouse, Rat
Conjugate
No Conjugate
Immunogen
Recombinant STAT2 (Arg587~Ile838) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2059230
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Lane1: Rat Serum; Lane2: Mouse Lung Tissue.)

Western Blot (WB) (Western Blot: Sample: Lane1: Rat Serum; Lane2: Mouse Lung Tissue.)

Western Blot (WB)

(Western Blot: Sample: Recombinant STAT2, Rat.)

Western Blot (WB) (Western Blot: Sample: Recombinant STAT2, Rat.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Rat Spinal Cord Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Rat Spinal Cord Tissue.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Rat Stomach Tissue)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Rat Stomach Tissue)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Rat Liver Tissue)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Rat Liver Tissue)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
96,857 Da
NCBI Official Full Name
signal transducer and activator of transcription 2
NCBI Official Synonym Full Names
signal transducer and activator of transcription 2
NCBI Official Symbol
Stat2
NCBI Protein Information
signal transducer and activator of transcription 2
UniProt Protein Name
Signal transducer and activator of transcription
UniProt Gene Name
Stat2

Uniprot Description

STAT2: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Binds to the IFN-stimulated response element (ISRE) and to the Gas element. This multiprotein transcription factor is termed ISGF3. Two alternatively spliced isoforms have been described.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 7q11

Cellular Component: cytoplasm; cytosol; nucleus; plasma membrane

Molecular Function: DNA binding; DNA binding transcription factor activity; identical protein binding; signal transducer activity

Biological Process: defense response to virus; regulation of protein amino acid phosphorylation; regulation of transcription, DNA-templated; transcription, DNA-dependent

Research Articles on STAT2

Similar Products

Product Notes

The STAT2 stat2 (Catalog #AAA2026299) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Signal Transducer And Activator Of Transcription 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/ml Immunocytochemistry in formalin fixed cells: 5-20ug/ml Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml Immunohistochemistry in paraffin section: 5-20ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the STAT2 stat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- RRLL KKMVSGTFLL RFSETSEGGI TCSWVEHQDD DKVLIYSVQP YTKEVLQSLP LTEIIRHYQV LAEENAPENP LRFLYPRVPR DEAFGCYYQE KVNLEERRKY LKHRLIVISN RQADELQQPL ELKQDPESLE LDAELMSVME LARDLELQSM LQVGLDLGVE PKPDPTLSPA PQILLEPDPA RALNQLLPEP DLPQDLQQLN TGEMEIFRNN INIDDVMPYG DPVLAGQSII EEAYRSCPSH FDVDGPLI. It is sometimes possible for the material contained within the vial of "Signal Transducer And Activator Of Transcription 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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