Western Blot (WB)
(Western Blot analysis of SGPL1 expression in transfected 293T cell line by SGPL1 polyclonal antibody. Lane 1: SGPL1 transfected lysate (63.5kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human SGPL1 Polyclonal Antibody | anti-SGPL1 antibody
SGPL1 (Sphingosine-1-phosphate Lyase 1, SP-lyase 1, S1PL, SPL 1, SPL, hSPL, KIAA1252, Sphingosine-1-phosphate Aldolase) APC
Western Blot (WB)
(Western Blot analysis of SGPL1 expression in transfected 293T cell line by SGPL1 polyclonal antibody. Lane 1: SGPL1 transfected lysate (63.5kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of SGPL1 expression in transfected 293T cell line by SGPL1 polyclonal antibody. Lane 1: SGPL1 transfected lysate (63.5kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
Uniprot Description
SGPL1: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
Protein type: Lipid Metabolism - sphingolipid; Apoptosis; EC 4.1.2.27; Membrane protein, integral; Lyase
Chromosomal Location of Human Ortholog: 10q21
Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to endoplasmic reticulum membrane
Molecular Function: protein binding; sphinganine-1-phosphate aldolase activity; carboxy-lyase activity; pyridoxal phosphate binding
Biological Process: estrogen metabolic process; sphingolipid metabolic process; sphingolipid biosynthetic process; androgen metabolic process; regulation of multicellular organism growth; platelet-derived growth factor receptor signaling pathway; palate development; fatty acid metabolic process; sphingolipid catabolic process; post-embryonic development; Leydig cell differentiation; skeletal morphogenesis; luteinization; spermatogenesis; hemopoiesis; vasculogenesis; kidney development; ceramide metabolic process
Research Articles on SGPL1
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Product Notes
The SGPL1 sgpl1 (Catalog #AAA6394026) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SGPL1 (Sphingosine-1-phosphate Lyase 1, SP-lyase 1, S1PL, SPL 1, SPL, hSPL, KIAA1252, Sphingosine-1-phosphate Aldolase) APC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SGPL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SGPL1 sgpl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGPL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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