Rabbit anti-Human SFTPA2B Polyclonal Antibody | anti-SFTPA2B antibody
SFTPA2B, CT (SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B, Pulmonary surfactant-associated protein A2, 35kD pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
NCBI and Uniprot Product Information
NCBI Description
DISCONTINUED: This record has been withdrawn by the HUGO Gene Nomenclature Committee (HGNC), and it has been determined that the sequence is redundant with SFTPA2 (GeneID:729238) in the GRCh37.1 reference assembly.
Uniprot Description
Function: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
Subunit structure: Oligomeric complex of 6 set of homotrimers.
Subcellular location: Secreted › extracellular space › extracellular matrix. Secreted › extracellular space › surface film.
Polymorphism: At least 6 alleles of SFTPA2 are known: 1A, 1A0, 1A1, 1A2, 1A3 and 1A4. The sequence shown is that of allele 1A0.
Involvement in disease: Pulmonary fibrosis, idiopathic (IPF) [MIM:178500]: A lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. In some cases, the disorder can be rapidly progressive and characterized by sequential acute lung injury with subsequent scarring and end-stage lung disease.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.9
Miscellaneous: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).
Sequence similarities: Belongs to the SFTPA family.Contains 1 C-type lectin domain.Contains 1 collagen-like domain.
Research Articles on SFTPA2B
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Product Notes
The SFTPA2B sftpa2 (Catalog #AAA649245) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SFTPA2B, CT (SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B, Pulmonary surfactant-associated protein A2, 35kD pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SFTPA2B can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the SFTPA2B sftpa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SFTPA2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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