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Western Blot (WB) (SFTPA2B Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SFTPA2B antibody detected the SFTPA2B protein (arrow).)

Rabbit anti-Human SFTPA2B Polyclonal Antibody | anti-SFTPA2B antibody

SFTPA2B, CT (SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B, Pulmonary surfactant-associated protein A2, 35kD pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5)

Gene Names
SFTPA2B; SP-2A; SP-A1; SP-A2; SPAII; SFTPA2; AC068139.3
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
SFTPA2B; Polyclonal Antibody; CT (SFTPA2; COLEC5; PSAP; SFTP1; SFTPA; Pulmonary surfactant-associated protein A2; 35kD pulmonary surfactant-associated protein; Alveolar proteinosis protein; Collectin-5); Anti -SFTPA2B; anti-SFTPA2B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-SFTPA2B antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
SFTPA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the C-terminal region of human SFTPA2B.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SFTPA2B Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SFTPA2B antibody detected the SFTPA2B protein (arrow).)

Western Blot (WB) (SFTPA2B Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SFTPA2B antibody detected the SFTPA2B protein (arrow).)
Related Product Information for anti-SFTPA2B antibody
This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.
Product Categories/Family for anti-SFTPA2B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
26,182 Da
NCBI Official Full Name
Surfactant protein A2B
NCBI Official Synonym Full Names
surfactant protein A2B
NCBI Official Symbol
SFTPA2B
NCBI Official Synonym Symbols
SP-2A; SP-A1; SP-A2; SPAII; SFTPA2; AC068139.3
NCBI Protein Information
surfactant protein A2B; SP-2A beta; SP-A1 beta; surfactant pulmonary associated protein A2; surfactant, pulmonary-associated protein A2B
UniProt Protein Name
Pulmonary surfactant-associated protein A2
UniProt Gene Name
SFTPA2
UniProt Synonym Gene Names
COLEC5; PSAP; SFTP1; SFTPA; SFTPA2B; PSP-A; PSPA; SP-A; SP-A2
UniProt Entry Name
SFPA2_HUMAN

NCBI Description

DISCONTINUED: This record has been withdrawn by the HUGO Gene Nomenclature Committee (HGNC), and it has been determined that the sequence is redundant with SFTPA2 (GeneID:729238) in the GRCh37.1 reference assembly.

Uniprot Description

Function: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

Subunit structure: Oligomeric complex of 6 set of homotrimers.

Subcellular location: Secreted › extracellular space › extracellular matrix. Secreted › extracellular space › surface film.

Polymorphism: At least 6 alleles of SFTPA2 are known: 1A, 1A0, 1A1, 1A2, 1A3 and 1A4. The sequence shown is that of allele 1A0.

Involvement in disease: Pulmonary fibrosis, idiopathic (IPF) [MIM:178500]: A lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. In some cases, the disorder can be rapidly progressive and characterized by sequential acute lung injury with subsequent scarring and end-stage lung disease.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.9

Miscellaneous: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).

Sequence similarities: Belongs to the SFTPA family.Contains 1 C-type lectin domain.Contains 1 collagen-like domain.

Research Articles on SFTPA2B

Similar Products

Product Notes

The SFTPA2B sftpa2 (Catalog #AAA649245) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SFTPA2B, CT (SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B, Pulmonary surfactant-associated protein A2, 35kD pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SFTPA2B can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the SFTPA2B sftpa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SFTPA2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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