Western Blot (WB)
(SFRS2B Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SFRS2B antibody detected the SFRS2B protein (arrow).)
Rabbit anti-Human, mouse SFRS2B Polyclonal Antibody | anti-SRSF8 antibody
SFRS2B Antibody (N-term)
Gene Names
SRSF8; DSM-1; SRP46; SFRS2B
Reactivity
Human, mouse
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SFRS2B; Polyclonal Antibody; SFRS2B Antibody (N-term); Serine/arginine-rich splicing factor 8; Pre-mRNA-splicing factor SRP46; Splicing factor SRp46; Splicing factor; arginine/serine-rich 2B; SRSF8; SRP46; anti-SRSF8 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SFRS2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human SFRS2B.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.35 (varies by lot)
Sequence Positions
45-73
Sequence Length
282
Applicable Applications for anti-SRSF8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(SFRS2B Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SFRS2B antibody detected the SFRS2B protein (arrow).)
Western Blot (WB)
(SFRS2B Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SFRS2B antibody detected the SFRS2B protein (arrow).)
Western Blot (WB)
(SFRS2B Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SFRS2B antibody detected the SFRS2B protein (arrow).)
Western Blot (WB)
(SFRS2B Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SFRS2B antibody detected the SFRS2B protein (arrow).)
Related Product Information for anti-SRSF8 antibody
The SR (serine/arginine-rich) family contains a number of
phosphoproteins that function as essential and alternative splicing
factors. The SR family of proteins is characterized by the presence
of a ribonucleoprotein (RNP)-type RNA binding motif and a
carboxyl-terminal arginine-serine-rich (RS) domain. The protein
encoded by this gene is a member of the SR family and functions as
an essential splicing factor in vitro. This gene is thought to be
an expressed PR264/SC35 retropseudogene.
phosphoproteins that function as essential and alternative splicing
factors. The SR family of proteins is characterized by the presence
of a ribonucleoprotein (RNP)-type RNA binding motif and a
carboxyl-terminal arginine-serine-rich (RS) domain. The protein
encoded by this gene is a member of the SR family and functions as
an essential splicing factor in vitro. This gene is thought to be
an expressed PR264/SC35 retropseudogene.
References
Manley, J.L., et al. Genes Dev. 24(11):1073-1074(2010)
Lareau, L.F., et al. Nature 446(7138):926-929(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Li, J., et al. Mol. Cell. Biol. 23(21):7437-7447(2003)
Grottke, C., et al. Int. J. Cancer 88(4):535-546(2000)
Lareau, L.F., et al. Nature 446(7138):926-929(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Li, J., et al. Mol. Cell. Biol. 23(21):7437-7447(2003)
Grottke, C., et al. Int. J. Cancer 88(4):535-546(2000)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32288
NCBI Official Full Name
serine/arginine-rich splicing factor 8
NCBI Official Synonym Full Names
serine/arginine-rich splicing factor 8
NCBI Official Symbol
SRSF8
NCBI Official Synonym Symbols
DSM-1; SRP46; SFRS2B
NCBI Protein Information
serine/arginine-rich splicing factor 8
UniProt Protein Name
Serine/arginine-rich splicing factor 8
Protein Family
UniProt Gene Name
SRSF8
UniProt Synonym Gene Names
SFRS2B; SRP46; Splicing factor SRp46
UniProt Entry Name
SRSF8_HUMAN
NCBI Description
This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Uniprot Description
SRp46: Involved in pre-mRNA alternative splicing. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 11q22
Cellular Component: nucleus
Molecular Function: protein binding; nucleotide binding
Biological Process: RNA splicing; mRNA processing
Similar Products
Product Notes
The SRSF8 srsf8 (Catalog #AAA9205632) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 45-73. The SFRS2B Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SFRS2B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SRSF8 srsf8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SFRS2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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