Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SEZ6L Polyclonal Antibody at dilution 1:30)
Rabbit SEZ6L Polyclonal Antibody | anti-SEZ6L antibody
SEZ6L Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
SEZ6L; Polyclonal Antibody; SEZ6L Polyclonal Antibody; anti-SEZ6L antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2mg/mL (varies by lot)
Sequence Length
948
Applicable Applications for anti-SEZ6L antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human SEZ6L
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SEZ6L Polyclonal Antibody at dilution 1:30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SEZ6L Polyclonal Antibody at dilution 1:30)
Related Product Information for anti-SEZ6L antibody
SEZ6L (seizure related 6 homolog-like) is a 1, 024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. Widely expressed, SEZ6L is a candidate tumor suppressor gene and may contribute to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi (CCP/SCR) domains, which may be involved in protein-protein interactions and signal transduction. The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
110,511 Da
NCBI Official Full Name
seizure 6-like protein isoform 6
NCBI Official Synonym Full Names
seizure related 6 homolog (mouse)-like
NCBI Official Symbol
SEZ6L
NCBI Protein Information
seizure 6-like protein; seizure related gene 6-like
UniProt Protein Name
Seizure 6-like protein
Protein Family
UniProt Gene Name
SEZ6L
UniProt Synonym Gene Names
KIAA0927
UniProt Entry Name
SE6L1_HUMAN
Uniprot Description
SEZ6L: May contribute to specialized endoplasmic reticulum functions in neurons. Belongs to the SEZ6 family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 22q12.1
Cellular Component: endoplasmic reticulum membrane; cell soma; integral to membrane
Biological Process: synapse maturation; adult locomotory behavior; cerebellar Purkinje cell layer development
Research Articles on SEZ6L
Similar Products
Product Notes
The SEZ6L sez6l (Catalog #AAA2530227) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SEZ6L Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SEZ6L can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100. Researchers should empirically determine the suitability of the SEZ6L sez6l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEZ6L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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