Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RNF185 Polyclonal Antibody at dilution 1:25)
Rabbit RNF185 Polyclonal Antibody | anti-RNF185 antibody
RNF185 Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
RNF185; Polyclonal Antibody; RNF185 Polyclonal Antibody; anti-RNF185 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.5mg/mL (varies by lot)
Sequence Length
192
Applicable Applications for anti-RNF185 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:10-1:50
Immunogen
Recombinant protein of human RNF185
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RNF185 Polyclonal Antibody at dilution 1:25)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RNF185 Polyclonal Antibody at dilution 1:25)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using RNF185 Polyclonal Antibody at dilution 1:25)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using RNF185 Polyclonal Antibody at dilution 1:25)
Related Product Information for anti-RNF185 antibody
RNF185 (ring finger protein 185), also known as FLJ38628, is a 192 amino acid multi-pass membrane protein containing one RING-type zinc finger. Two RNF185 isoforms exist as a result of alternative splicing, and the gene encoding RNF185 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
14,139 Da
NCBI Official Full Name
RNF185, partial
NCBI Official Synonym Full Names
ring finger protein 185
NCBI Official Symbol
RNF185
NCBI Protein Information
E3 ubiquitin-protein ligase RNF185; BSK65-MONO1; BSK65-MONO2; BSK65-PANC1; BSK65-PANC2; BSK65-TEST1; BSK65-TEST2; BSK65-TEST3
UniProt Protein Name
E3 ubiquitin-protein ligase RNF185
Protein Family
UniProt Gene Name
RNF185
UniProt Entry Name
RN185_HUMAN
Uniprot Description
RNF185: Mitochondrial E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Ubiquitin conjugating system; Ligase; Ubiquitin ligase; EC 6.3.2.-
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component: mitochondrial outer membrane; endoplasmic reticulum membrane; integral to membrane
Molecular Function: zinc ion binding; ligase activity
Biological Process: protein ubiquitination; autophagy
Research Articles on RNF185
Similar Products
Product Notes
The RNF185 rnf185 (Catalog #AAA2525905) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RNF185 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RNF185 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:10-1:50. Researchers should empirically determine the suitability of the RNF185 rnf185 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RNF185, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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