Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat heart using Serpina1 Polyclonal Antibody at dilution of 1:100)
Rabbit anti-Rat SERPINA1 Polyclonal Antibody | anti-SERPINA1 antibody
SERPINA1 Polyclonal Antibody
Gene Names
Serpina1; Pi; AAT; Spi1
Reactivity
Rat
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
SERPINA1; Polyclonal Antibody; SERPINA1 Polyclonal Antibody; A1A; A1AT; AAT; Alpha 1 antiproteinase; Alpha 1 antitrypsin; Alpha 1 antitrypsin null; Alpha 1 protease inhibitor; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; alpha1 proteinase inhibitor; Alpha1AT; Dom1; PI; PI1; PRO2275; Serine (or cysteine) proteinase inhibitor clade A member 1; Serine protease inhibitor 1-1; Serine protease inhibitor A1a; Serpin A1; Serpin A1a; Serpin peptidase inhibitor clade A member 1; Serpina1; Short peptide from AAT; SPAAT; Spi1-1; anti-SERPINA1 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration
1 mg/mL (varies by lot)
Sequence Length
411
Applicable Applications for anti-SERPINA1 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:100-1:200
Immunogen
Recombinant Rat Alpha-1-antiproteinase protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat heart using Serpina1 Polyclonal Antibody at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat heart using Serpina1 Polyclonal Antibody at dilution of 1:100)
Related Product Information for anti-SERPINA1 antibody
SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT), which is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. AAT is a glycoprotein synthesized primarily by hepatocytes, with smaller amountssynthesized by intestinal epithelial cells, neutrophils, pulmonary alveolar cells and macrophages. AAT is the most abundant, endogenous serine protease inhibitor in blood circulation and it has been implicated in regulating vital fluid phase biological events such as blood coagulation, fibrinolysis, complement activation, apoptosis, reproduction, tumor progression and inflammatory response. The primary function of AAT is thought to be the inactivation of neutrophil elastase and other endogenous serine proteases. Defects in SERPINA1 can cause emphysema or liver disease.
Product Categories/Family for anti-SERPINA1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,136 Da
NCBI Official Full Name
alpha-1-antiproteinase
NCBI Official Synonym Full Names
serpin family A member 1
NCBI Official Symbol
Serpina1
NCBI Official Synonym Symbols
Pi; AAT; Spi1
NCBI Protein Information
alpha-1-antiproteinase
UniProt Protein Name
Alpha-1-antiproteinase
Protein Family
UniProt Gene Name
Serpina1
Uniprot Description
Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin.
Research Articles on SERPINA1
Similar Products
Product Notes
The SERPINA1 serpina1 (Catalog #AAA2554111) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SERPINA1 Polyclonal Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SERPINA1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:100-1:200. Researchers should empirically determine the suitability of the SERPINA1 serpina1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERPINA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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