Rabbit SERP1 Polyclonal Antibody | anti-SERP1 antibody

SERP1 Polyclonal Antibody

Cat. Num. AAA3006481

• Gene Names: SERP1; RAMP4
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: SERP1; Polyclonal Antibody; SERP1 Polyclonal Antibody; Stress-associated endoplasmic reticulum protein 1; Ribosome-attached membrane protein 4; RAMP4; anti-SERP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: SERP1 polyclonal antibody detects endogenous levels of SERP1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 66

• Applicable Applications for anti-SERP1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human SERP1.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of SERP1 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264. 7 whole cell lysateLane3:PC12 whole cell lysate)

Related Product Information for anti-SERP1 antibody

Newly synthesized proteins emerging through the endoplasmic reticulum (ER) membrane enter a unique environment for folding and assembly by associated proteins. RAMP4 (ribosome-attached membrane protein 4), also designated SERP1 (stress-associated endoplasmic reticulum protein family member 1) and RAMP4-2 (ribosome-associated membrane protein 4-2), also known as SERP2 (stress-associated endoplasmic reticulum protein family member 2), are single-pass type IV membrane proteins that localize to the ER and belong to the RAMP4 family. RAMP4 and RAMP4-2 may interact with target proteins during translocation into the lumen of the ER and protect unfolded target proteins against degradation during ER stress. After termination of ER stress, RAMP4 and RAMP4-2 are involved in facilitating glycosylation of target proteins. RAMP4 consists of 66 amino acids and is encoded by a gene located on human chromosome 3, whereas RAMP4-2 is encoded by a gene located on human chromosome 13 and is composed of 61 amino acids.

NCBI and Uniprot Product Information

• NCBI GI #: 7657552
• NCBI GeneID: 27230
• NCBI Accession #: NP_055260.1
• NCBI GenBank Nucleotide #: NP_055260.1
• UniProt Accession #: Q9Y6X1
• Molecular Weight: ~ 11kDa
• NCBI Official Full Name: stress-associated endoplasmic reticulum protein 1
• NCBI Official Synonym Full Names: stress associated endoplasmic reticulum protein 1
• NCBI Official Symbol: SERP1
• NCBI Official Synonym Symbols: RAMP4
• NCBI Protein Information: stress-associated endoplasmic reticulum protein 1
• UniProt Protein Name: Stress-associated endoplasmic reticulum protein 1
• Protein Family: Stress-associated endoplasmic reticulum protein
• UniProt Gene Name: SERP1
• UniProt Synonym Gene Names: RAMP4

Uniprot Description

Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins ().