Western Blot (WB)
((1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat SEPT6 Polyclonal Antibody | anti-SEPT6 antibody
Goat anti-SEPT6 Antibody
Immunohistochemistry: In paraffin embedded Human Tonsil shows specific staining in dividing cells just outside a germinal centre. Recommended concentration, 3-5ug/ml.
Western Blot: Approx 50kDa band observed in Human Testis, Thyroid Gland and MOLT4 cell lysates (calculated MW of 49.7kDa according to NP_055944.2). Recommended concentration: 0. 03-1ug/ml.
Western Blot (WB)
((1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Immunohistochemistry (IHC)
((3.8ug/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)
Immunohistochemistry (IHC)
((3.8ug/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
SEPT6: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Belongs to the septin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Cytoskeletal
Chromosomal Location of Human Ortholog: Xq24
Cellular Component: cleavage furrow; midbody; nerve terminal; spindle; synaptic vesicle
Molecular Function: GTP binding; protein binding
Biological Process: cytokinesis; viral reproduction
Research Articles on SEPT6
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Product Notes
The SEPT6 sept6 (Catalog #AAA421879) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-SEPT6 Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Cow, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's SEPT6 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA: Antibody detection limit dilution 1: 4000. Immunohistochemistry: In paraffin embedded Human Tonsil shows specific staining in dividing cells just outside a germinal centre. Recommended concentration, 3-5ug/ml. Western Blot: Approx 50kDa band observed in Human Testis, Thyroid Gland and MOLT4 cell lysates (calculated MW of 49.7kDa according to NP_055944.2). Recommended concentration: 0. 03-1ug/ml. Researchers should empirically determine the suitability of the SEPT6 sept6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: DEVNAFKQRK TA. It is sometimes possible for the material contained within the vial of "SEPT6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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