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SDS-Page

HSPB3 recombinant protein

HSPB3, 1-150aa, Human, His tag, E Coli (Denatured)

Gene Names
HSPB3; HMN2C; DHMN2C; HSPL27
Applications
SDS-Page
Purity
> 85% by SDS-PAGE
Synonyms
HSPB3; 1-150aa; Human; His tag; E Coli (Denatured); Heat shock protein beta-3; DHMN2C; HMN2C; HSPL27; HSPB3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 85% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0), 5% glycerol, 1M urea.
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MAKIILRHLI EIPVRYQEEF EARGLEDCRL DHALYALPGP TIVDLRKTRA AQSPPVDSAA ETPPREGKSH FQILLDVVQF LPEDIIIQTF EGWLLIKAQH GTRMDEHGFI SRSFTRQYKL PDGVEIKDLS AVLCHDGILV VEVKDPVGTK
Sequence Length
150
Applicable Applications for HSPB3 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for HSPB3 recombinant protein
HSPB3, also known as HSPL27, is a muscle-specific small heat shock protein. It is expressed preferentially in heart and skeletal muscle. Mammalian small heat shock proteins (sHSP) is a abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB3 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also Inhibitor of actin polymerization.
Product Categories/Family for HSPB3 recombinant protein
References
Fontaine JM., et al. (2005) Biochem Biophys Res Commun. 337 (3):1006-11.; Suqiyama Y., et al. (2000) J Biol Chem. 275 (2):1095-104.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19.1 kDa (170aa)
NCBI Official Full Name
heat shock protein beta-3
NCBI Official Synonym Full Names
heat shock protein family B (small) member 3
NCBI Official Symbol
HSPB3
NCBI Official Synonym Symbols
HMN2C; DHMN2C; HSPL27
NCBI Protein Information
heat shock protein beta-3
UniProt Protein Name
Heat shock protein beta-3
Protein Family
UniProt Gene Name
HSPB3
UniProt Synonym Gene Names
HSP27; HSPL27; HspB3; HSP 17

NCBI Description

This gene encodes a muscle-specific small heat shock protein. A mutation in this gene is the cause of autosomal dominant distal hereditary motor neuropathy type 2C.[provided by RefSeq, Sep 2010]

Uniprot Description

Inhibitor of actin polymerization.

Research Articles on HSPB3

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Product Notes

The HSPB3 hspb3 (Catalog #AAA204611) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's HSPB3 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the HSPB3 hspb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MAKIILRHLI EIPVRYQEEF EARGLEDCRL DHALYALPGP TIVDLRKTRA AQSPPVDSAA ETPPREGKSH FQILLDVVQF LPEDIIIQTF EGWLLIKAQH GTRMDEHGFI SRSFTRQYKL PDGVEIKDLS AVLCHDGILV VEVKDPVGTK. It is sometimes possible for the material contained within the vial of "HSPB3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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