Rabbit Semaphorin 3F Polyclonal Antibody | anti-SEMA3F antibody

Semaphorin 3F polyclonal antibody

Cat. Num. AAA3013838

• Gene Names: SEMA3F; SEMA4; SEMAK; SEMA-IV
• Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep
• Applications: Western Blot
• Purity: affinity purified by Protein A
• Synonyms: Semaphorin 3F; Polyclonal Antibody; Semaphorin 3F polyclonal antibody; Semaphorin-3F; Semaphorin3F; Sema III/F; Sema IV; sema3F; SemaIII/F; SemaIV; Semaphorin IV; SemaphorinIV; SEM3F_HUMAN; anti-SEMA3F antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep
• Clonality: Polyclonal
• Specificity: Semaphorin 3F polyclonal Antibody detects endogenous levels of Semaphorin 3F protein.
• Purity/Purification: affinity purified by Protein A
• Form/Format: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Applicable Applications for anti-SEMA3F antibody: Western Blot (WB)
• Application Notes: WB: 1:500-2000
• Immunogen: KLH conjugated synthetic peptide derived from human Sema3F:201-300/785
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Testing Data

(Anti-Semaphorin 3F at 1/1000 dilution)

Testing Data

(Anti-Semaphorin 3F at 1/300 dilution)

Testing Data

(Anti-Semaphorin 3F at 1/500 dilution)

Testing Data

(Anti- Semaphorin 3F at 1/1000 dilution)

Related Product Information for anti-SEMA3F antibody

The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.

NCBI and Uniprot Product Information

• NCBI GI #: 188497703
• NCBI GeneID: 6405
• NCBI Accession #: NP_004177.3
• NCBI GenBank Nucleotide #: NM_004186.4
• UniProt Accession #: Q13275; Q13274; Q13372; Q15704; Q6GTR4; C9JQ85
• Molecular Weight: 85,064 Da
• NCBI Official Full Name: semaphorin-3F isoform 1
• NCBI Official Synonym Full Names: semaphorin 3F
• NCBI Official Symbol: SEMA3F
• NCBI Official Synonym Symbols: SEMA4; SEMAK; SEMA-IV
• NCBI Protein Information: semaphorin-3F
• UniProt Protein Name: Semaphorin-3F
• Protein Family: Semaphorin
• UniProt Gene Name: SEMA3F
• UniProt Synonym Gene Names: Sema IV

NCBI Description

This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Uniprot Description

May play a role in cell motility and cell adhesion.