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Immunohistochemistry (IHC)

Rabbit anti-Human SCP2 Polyclonal Antibody | anti-SCP2 antibody

Anti-SCP2 Antibody

Gene Names
SYCP2; SCP2
Reactivity
Human
Applications
Western Blot
Purity
Affinity purification. The antibody was purified by affinity chromatography
Synonyms
SCP2; Polyclonal Antibody; Anti-SCP2 Antibody; Synaptonemal complex protein 2; SCP-2; Synaptonemal complex lateral element protein; hsSCP2; SYCP2; anti-SCP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Polyclonal Antibody to detect endogenous levels of SCP3 in human samples
Purity/Purification
Affinity purification. The antibody was purified by affinity chromatography
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH7.3; 30% glycerol and 0.01% sodium azide
Applicable Applications for anti-SCP2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of SCP2
Positive Control
WB: Jurkat; PC3; U937; MCF7 whole cell lysates.
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months

Immunohistochemistry (IHC)

Immunohistochemistry (IHC)
Related Product Information for anti-SCP2 antibody
Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.
Product Categories/Family for anti-SCP2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
175,639 Da
NCBI Official Full Name
SYCP2 protein, partial
NCBI Official Synonym Full Names
synaptonemal complex protein 2
NCBI Official Symbol
SYCP2
NCBI Official Synonym Symbols
SCP2
NCBI Protein Information
synaptonemal complex protein 2; SCP-2; hsSCP2; synaptonemal complex lateral element protein
UniProt Protein Name
Synaptonemal complex protein 2
UniProt Gene Name
SYCP2
UniProt Synonym Gene Names
SCP2; SCP-2; hsSCP2
UniProt Entry Name
SYCP2_HUMAN

NCBI Description

The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]

Uniprot Description

SYCP2: Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements. Belongs to the SYCP2 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: lateral element; synaptonemal complex; nucleus

Molecular Function: DNA binding; protein heterodimerization activity

Biological Process: synaptonemal complex assembly; fertilization; cell division; male genitalia morphogenesis; female meiosis; male meiosis; negative regulation of apoptosis

Research Articles on SCP2

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Product Notes

The SCP2 sycp2 (Catalog #AAA847286) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SCP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SCP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the SCP2 sycp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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