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Western Blot (WB) (Anti-SCML2 rabbit polyclonal antibody at 1:500 dilutionLane A: Hela Whole Cell LysateLane B: 293T Whole Cell LysateLane C: Jurkat Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti- Rabbit  IgG H&L (Dylight 800)  at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:77 kDaObserved band size:70 kDa(We are unsure as to the identity of these extra bands.))

Rabbit anti-Human SCML2 Polyclonal Antibody | anti-SCML2 antibody

Anti-SCML2 Antibody, Rabbit Polyclonal

Reactivity
Human
Applications
Western Blot
Purity
Protein A & Antigen Affinity
Synonyms
SCML2; Polyclonal Antibody; Anti-SCML2 Antibody; Rabbit Polyclonal; SCML2 Antibody; Rabbit PAb; Antigen Affinity Purified; sex comb on midleg-like 2 (Drosophila); anti-SCML2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SCML2
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-SCML2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human SCML2
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human SCML2, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Anti-SCML2 rabbit polyclonal antibody at 1:500 dilutionLane A: Hela Whole Cell LysateLane B: 293T Whole Cell LysateLane C: Jurkat Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti- Rabbit  IgG H&L (Dylight 800)  at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:77 kDaObserved band size:70 kDa(We are unsure as to the identity of these extra bands.))

Western Blot (WB) (Anti-SCML2 rabbit polyclonal antibody at 1:500 dilutionLane A: Hela Whole Cell LysateLane B: 293T Whole Cell LysateLane C: Jurkat Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti- Rabbit  IgG H&L (Dylight 800)  at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:77 kDaObserved band size:70 kDa(We are unsure as to the identity of these extra bands.))
Related Product Information for anti-SCML2 antibody
SCML2-dependent H3K27me3 in the male germline prepares the expression of developmental regulator and somatic genes in embryonic development. SCML2, a germline-specific subunit of a Polycomb repressive complex 1 (PRC1), establishes the unique epigenome of the male germline through two distinct antithetical mechanisms. SCML2/USP7 complex constitutes a novel molecular pathway in modulating the epigenetic state of sex chromosomes during male meiosis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15,471 Da
NCBI Official Full Name
Homo sapiens sex comb on midleg-like 2 (Drosophila) (SCML2), transcript variant 1, mRNA
NCBI Official Synonym Full Names
sex comb on midleg-like 2 (Drosophila)
NCBI Official Symbol
SCML2
NCBI Protein Information
sex comb on midleg-like protein 2
UniProt Protein Name
Sex comb on midleg-like protein 2
UniProt Gene Name
SCML2
UniProt Entry Name
SCML2_HUMAN

NCBI Description

This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010]

Uniprot Description

SCML2: a protein of unknown function. Contains a SAM (sterile alpha motif) and two MBT domains.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: PcG protein complex; nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: anatomical structure morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on SCML2

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Product Notes

The SCML2 scml2 (Catalog #AAA8101503) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SCML2 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SCML2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the SCML2 scml2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCML2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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