Rabbit anti-Human SCD5 Polyclonal Antibody | anti-SCD5 antibody

SCD5, ID (SCD5, ACOD4, SCD4, Stearoyl-CoA desaturase 5, Acyl-CoA-desaturase 4, HSCD5, Stearoyl-CoA 9-desaturase)

Cat. Num. AAA6003755

• Gene Names: SCD5; SCD2; SCD4; ACOD4; FADS4; HSCD5
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SCD5; Polyclonal Antibody; ID (SCD5; ACOD4; SCD4; Stearoyl-CoA desaturase 5; Acyl-CoA-desaturase 4; HSCD5; Stearoyl-CoA 9-desaturase); Anti -SCD5; anti-SCD5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-SCD5 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: SCD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the Central region of human SCD5.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SCD5 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SCD5 antibody detected the SCD5 protein (arrow).)

Related Product Information for anti-SCD5 antibody

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).

Product Categories/Family for anti-SCD5 antibody

Antibodies; Abs to Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 148596961
• NCBI GeneID: 79966
• NCBI Accession #: NP_001032671.2
• NCBI GenBank Nucleotide #: NM_001037582.2
• UniProt Accession #: Q86SK9; Q4W5Q5; Q8NDS0; Q9H7D1; B2RPG0
• Molecular Weight: 37,610 Da
• NCBI Official Full Name: stearoyl-CoA desaturase 5 isoform a
• NCBI Official Synonym Full Names: stearoyl-CoA desaturase 5
• NCBI Official Symbol: SCD5
• NCBI Official Synonym Symbols: SCD2; SCD4; ACOD4; FADS4; HSCD5
• NCBI Protein Information: stearoyl-CoA desaturase 5; acyl-CoA-desaturase 4; stearoyl-CoA 9-desaturase; stearoyl-CoA desaturase 4
• UniProt Protein Name: Stearoyl-CoA desaturase 5
• Protein Family: Stearoyl-CoA desaturase
• UniProt Gene Name: SCD5
• UniProt Synonym Gene Names: ACOD4; SCD4
• UniProt Entry Name: SCD5_HUMAN

NCBI Description

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008]

Uniprot Description

SCD5: Fatty acid delta-9-desaturase that introduces a double bond in fatty acyl-coenzyme A at the delta-9 position. Belongs to the fatty acid desaturase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 1.14.19.1; Oxidoreductase

Chromosomal Location of Human Ortholog: 4q21.22

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: iron ion binding; stearoyl-CoA 9-desaturase activity

Biological Process: fatty acid biosynthetic process