Rabbit anti-SARS-CoV SARS Spike Protein Polyclonal Antibody | anti-SARS antibody
SARS Spike Protein Polyclonal Antibody
Gene Names
S; E2
Reactivity
SARS-CoV
Applications
ELISA
Synonyms
SARS Spike Protein; Polyclonal Antibody; SARS Spike Protein Polyclonal Antibody; anti-SARS antibody
Host
Rabbit
Reactivity
SARS-CoV
Clonality
Polyclonal
Specificity
SARS-CoV spike protein.
Form/Format
Antibody purified by peptide affinity chromatography in PBS, 0.02% sodium azide
Applicable Applications for anti-SARS antibody
ELISA (EIA)
Application Notes
ELISA: Endusers should determine optimal antibody concentrations for their samples and assay formats.
Antigen
Synthetic peptide corresponding to amino acids at the center of SARS-CoV spike protein.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Related Product Information for anti-SARS antibody
Background: Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus referred to as SARS-associated coronavirus (SARS-CoV). SARS was first reported in Asia in February 2003. Over the next few months, the illness spread to more than two dozen countries in North America, South America, Europe, and Asia before the SARS global outbreak of 2003 was contained. SARS-CoV is transmitted from person to person by close personal contact such as via respiratory droplets produced when an infected person coughs or sneezes. The genomes of these viruses are positive-stranded RNA approximately 27-31kb long. SARS-CoV spike (S) protein has two major biological functions: 1) mediating receptor (angiotensin converting enzyme 2, ACE2) binding and membrane fusion; 2) inducing neutralizing antibody responses.
Product Categories/Family for anti-SARS antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
139,125 Da
NCBI Official Full Name
Spike glycoprotein
NCBI Official Symbol
S
NCBI Official Synonym Symbols
E2
NCBI Protein Information
E2 glycoprotein precursor; spike glycoprotein
UniProt Protein Name
Spike glycoprotein
Protein Family
UniProt Gene Name
S
UniProt Synonym Gene Names
S glycoprotein
UniProt Entry Name
SPIKE_CVHSA
Uniprot Description
S1 attaches the virion to the cell membrane by interacting with human ACE2 and CLEC4M/DC-SIGNR, initiating the infection. Binding to the receptor and internalization of the virus into the endosomes of the host cell probably induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
Research Articles on SARS
Similar Products
Product Notes
The SARS s (Catalog #AAA191598) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SARS Spike Protein Polyclonal Antibody reacts with SARS-CoV and may cross-react with other species as described in the data sheet. AAA Biotech's SARS Spike Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: Endusers should determine optimal antibody concentrations for their samples and assay formats. Researchers should empirically determine the suitability of the SARS s for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SARS Spike Protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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