Testing Data #1
(Western blot analysis of whole cell lysates fro Daudi B-lymphoblastoid cels probed with Rabbit anti Human SARM1 (MBS221761) at 0.5(A), 1(B) and 2(C) ug/ml)
Rabbit anti-Mouse SARM1 Polyclonal Antibody | anti-SARM1 antibody
RABBIT ANTI SARM1
Gene Names
SARM1; SARM; SAMD2; MyD88-5
Reactivity
Mouse
Applications
Western Blot
Synonyms
SARM1; Polyclonal Antibody; RABBIT ANTI SARM1; anti-SARM1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This item is specific for human SARM1 (sterile alpha and TIR motif containing 1).
SARM1 contains a Toll-interleukin-1 (TIR) domain, and is reported to serve as an adaptor protein for the Toll-like receptors during the innate immune response.
SARM1 contains a Toll-interleukin-1 (TIR) domain, and is reported to serve as an adaptor protein for the Toll-like receptors during the innate immune response.
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
724
Applicable Applications for anti-SARM1 antibody
Western Blot (WB)
Application Notes
Western Blot: This item detects a band of approximately 80 kDa in Daudi cell lysates.
Western Blotting: Minimum Dilution: 0.5ug/ml; Maximum Dilution: 2.0ug/ml
Western Blotting: Minimum Dilution: 0.5ug/ml; Maximum Dilution: 2.0ug/ml
Perservative Stabilisers
0.02% Sodium Azide
Immunogen
Synthetic peptide corresponding to a region within the C-Terminus of human SARM1.
Buffer Solution
Buffer Solution
Antiserum Preparation
Antisera to human SARM1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Testing Data #1
(Western blot analysis of whole cell lysates fro Daudi B-lymphoblastoid cels probed with Rabbit anti Human SARM1 (MBS221761) at 0.5(A), 1(B) and 2(C) ug/ml)
Testing Data #1
(Western blot analysis of whole cell lysates fro Daudi B-lymphoblastoid cels probed with Rabbit anti Human SARM1 (MBS221761) at 0.5(A), 1(B) and 2(C) ug/ml)
Testing Data #2
(Immunocytochemical staining of Daudi cells with Rabbit anti Human SARM1 (MBS221761))
Testing Data #2
(Immunocytochemical staining of Daudi cells with Rabbit anti Human SARM1 (MBS221761))
Related Product Information for anti-SARM1 antibody
MBS221761 is specific for human SARM1 (sterile alpha and TIR motif containing 1). SARM1 contains a Toll-interleukin-1 (TIR) domain, and is reported to serve as an adaptor protein for the Toll-like receptors during the innate immune response.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75,337 Da
NCBI Official Full Name
sterile alpha and TIR motif-containing protein 1
NCBI Official Synonym Full Names
sterile alpha and TIR motif containing 1
NCBI Official Symbol
SARM1
NCBI Official Synonym Symbols
SARM; SAMD2; MyD88-5
NCBI Protein Information
sterile alpha and TIR motif-containing protein 1; SAM domain-containing protein 2; sterile alpha and Armadillo repeat protein; sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila; sterile alpha motif domain-containing protein 2; tir-1 homolog
UniProt Protein Name
Sterile alpha and TIR motif-containing protein 1
Protein Family
UniProt Gene Name
SARM1
UniProt Synonym Gene Names
KIAA0524; SAMD2; SARM; MyD88-5; SAM domain-containing protein 2
UniProt Entry Name
SARM1_HUMAN
Uniprot Description
SARM1: Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17q11
Cellular Component: microtubule; mitochondrion; axon; cytoplasm; dendrite; extrinsic to mitochondrial outer membrane; synapse; cytosol; cell junction
Biological Process: regulation of apoptosis; MyD88-independent toll-like receptor signaling pathway; regulation of dendrite morphogenesis; toll-like receptor signaling pathway; response to glucose stimulus; innate immune response; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway
Research Articles on SARM1
Similar Products
Product Notes
The SARM1 sarm1 (Catalog #AAA221761) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI SARM1 reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SARM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: This item detects a band of approximately 80 kDa in Daudi cell lysates. Western Blotting: Minimum Dilution: 0.5ug/ml; Maximum Dilution: 2.0ug/ml. Researchers should empirically determine the suitability of the SARM1 sarm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SARM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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