Western Blot (WB)
(Western blot analysis of SAMSN in Hela cell lysate with SAMSN antibody at (A) 0.5 and (B) 1 μg/mL.)
Rabbit anti-Human SAMSN Polyclonal Antibody | anti-SAMSN1 antibody
SAMSN Antibody
Gene Names
SAMSN1; SLy2; HACS1; NASH1; SASH2; SH3D6B
Reactivity
Human
Applications
ELISA, Western Blot, Immunocytochemistry, Immunofluorescence
Purity
SAMSN Antibody is affinity chromatography purified via peptide column.
Synonyms
SAMSN; Polyclonal Antibody; SAMSN Antibody; SLy2; HACS1; NASH1; SASH2; SH3D6B; SAM domain-containing protein SAMSN-1; Hematopoietic adaptor containing SH3 and SAM domains 1; SAM domain; SH3 domain and nuclear localization signals 1; anti-SAMSN1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
At least two isoforms of SAMSN are known to exist.
Purity/Purification
SAMSN Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
373
Applicable Applications for anti-SAMSN1 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
SAMSN antibody can be used for detection of SAMSN by Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal SAMSN antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SAMSN.
Buffer
SAMSN Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SAMSN antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of SAMSN in Hela cell lysate with SAMSN antibody at (A) 0.5 and (B) 1 μg/mL.)
Western Blot (WB)
(Western blot analysis of SAMSN in Hela cell lysate with SAMSN antibody at (A) 0.5 and (B) 1 μg/mL.)
Immunocytochemistry (IHC)
(Immunocytochemistry of SAMSN1 in HeLa cells with SAMSN1 antibody at 2.5 μg/ml.)
Immunocytochemistry (IHC)
(Immunocytochemistry of SAMSN1 in HeLa cells with SAMSN1 antibody at 2.5 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of SAMSN1 in HeLa cells with SAMSN1 antibody at 5 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of SAMSN1 in HeLa cells with SAMSN1 antibody at 5 μg/ml.)
Related Product Information for anti-SAMSN1 antibody
SAMSN Antibody: SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41 kDa
NCBI Official Full Name
SAM domain-containing protein SAMSN-1 isoform 1
NCBI Official Synonym Full Names
SAM domain, SH3 domain and nuclear localization signals 1
NCBI Official Symbol
SAMSN1
NCBI Official Synonym Symbols
SLy2; HACS1; NASH1; SASH2; SH3D6B
NCBI Protein Information
SAM domain-containing protein SAMSN-1; SH3-SAM adaptor protein; SAM and SH3 domain containing 2; hematopoietic adaptor containing SH3 and SAM domains 1; SAM domain, SH3 domain and nuclear localisation signals, 1; nuclear localization signals, SAM and SH3 domain containing 1; SAM domain, SH3 domain and nuclear localization signals protein 1; hematopoietic adapter-containing SH3 and sterile alpha-motif (SAM) domains 1; hematopoietic adapter-containing SH3 and sterile α-motif (SAM) domains 1; Src homology domain 3 (SH3)-containing adapter protein SH3 lymphocyte protein 2
UniProt Protein Name
SAM domain-containing protein SAMSN-1
Protein Family
UniProt Gene Name
SAMSN1
UniProt Synonym Gene Names
HACS1
UniProt Entry Name
SAMN1_HUMAN
NCBI Description
SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008]
Uniprot Description
SAMSN1: an adaptor and scaffold protein containing an SH3 and a SAM (sterile alpha motif) domain. Its expression is induced by B cell activation signals. Two alternatively spliced isoforms have been described.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 21q11
Cellular Component: ruffle; cytosol; nucleus
Molecular Function: phosphotyrosine binding
Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of adaptive immune response; negative regulation of B cell activation
Research Articles on SAMSN1
Similar Products
Product Notes
The SAMSN1 samsn1 (Catalog #AAA153721) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SAMSN Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SAMSN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF). SAMSN antibody can be used for detection of SAMSN by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the SAMSN1 samsn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SAMSN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
