Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat heart using MYO10 Polyclonal Antibody )
Rabbit MYO10 Polyclonal Antibody | anti-MYO10 antibody
MYO10 Polyclonal Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat heart using MYO10 Polyclonal Antibody )
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat heart using MYO10 Polyclonal Antibody )
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]
Uniprot Description
MYO10: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podosome belt in osteoclasts.
Protein type: Motor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5p15.1-p14.3
Cellular Component: ruffle; filopodium membrane; filopodium tip; neuron projection; cell soma; lamellipodium; cytoplasm; nucleolus; plasma membrane; cell cortex; cytosol; myosin complex
Molecular Function: actin filament binding; calmodulin binding; protein binding; phosphatidylinositol-3,4,5-triphosphate binding; spectrin binding; plus-end directed microfilament motor activity; actin-dependent ATPase activity; ATP binding
Biological Process: axon guidance; regulation of cell shape; metabolic process; positive regulation of cell-cell adhesion; innate immune response; regulation of filopodium formation; cytoskeleton-dependent intracellular transport
Research Articles on MYO10
Similar Products
Product Notes
The MYO10 myo10 (Catalog #AAA2566817) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MYO10 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MYO10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the MYO10 myo10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYO10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
