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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7128290(S1PR3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit anti-Human, Mouse S1PR3 Polyclonal Antibody | anti-S1PR3 antibody

S1PR3 Antibody

Gene Names
S1PR3; EDG3; LPB3; S1P3; EDG-3
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
S1PR3; Polyclonal Antibody; S1PR3 Antibody; Sphingosine-1-phosphate receptor 3; anti-S1PR3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-S1PR3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:10000
WB: 1:1000-1:5000
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human S1PR3
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7128290(S1PR3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7128290(S1PR3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7128290(S1PR3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7128290(S1PR3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

SDS-Page

(Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal brain tissue, Primary antibody: MBS7128290(S1PR3 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)

SDS-Page (Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal brain tissue, Primary antibody: MBS7128290(S1PR3 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)
Product Categories/Family for anti-S1PR3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,250 Da
NCBI Official Full Name
sphingosine 1-phosphate receptor 3
NCBI Official Synonym Full Names
sphingosine-1-phosphate receptor 3
NCBI Official Symbol
S1PR3
NCBI Official Synonym Symbols
EDG3; LPB3; S1P3; EDG-3
NCBI Protein Information
sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; sphingosine 1-phosphate receptor Edg-3; endothelial differentiation G-protein coupled receptor 3; G protein-coupled receptor, endothelial differentiation gene-3; en
UniProt Protein Name
Sphingosine 1-phosphate receptor 3
UniProt Gene Name
S1PR3
UniProt Synonym Gene Names
EDG3; S1P receptor 3; S1P3
UniProt Entry Name
S1PR3_HUMAN

NCBI Description

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008]

Uniprot Description

S1PR3: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 9q22.1-q22.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; integrin binding; lipid binding

Biological Process: G-protein coupled receptor protein signaling pathway; anatomical structure morphogenesis; elevation of cytosolic calcium ion concentration; regulation of interleukin-1 beta production; positive regulation of cell proliferation; cytokine production; G-protein signaling, adenylate cyclase inhibiting pathway; inflammatory response

Research Articles on S1PR3

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Product Notes

The S1PR3 s1pr3 (Catalog #AAA7128290) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The S1PR3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's S1PR3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:10000 WB: 1:1000-1:5000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the S1PR3 s1pr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S1PR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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