Rabbit anti-Mouse RUTBC1 Polyclonal Antibody | anti-RUTBC1 antibody

RUTBC1, CT (SGSM2, KIAA0397, RUTBC1, Small G protein signaling modulator 2, RUN and TBC1 domain-containing protein 1) (PE)

Cat. Num. AAA6344479

• Gene Names: SGSM2; RUTBC1
• Reactivity: Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RUTBC1; Polyclonal Antibody; CT (SGSM2; KIAA0397; Small G protein signaling modulator 2; RUN and TBC1 domain-containing protein 1) (PE); SGSM2; RUN and TBC1 domain-containing protein 1; anti-RUTBC1 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-RUTBC1 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:50-100; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: RUTBC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 962-992 amino acids from the C-terminal region of human RUTBC1.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(RUTBC1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RUTBC1 antibody detected the RUTBC1 protein (arrow).)

Immunohistochemistry (IHC)

(RUTBC1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RUTBC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-RUTBC1 antibody

The specific function of the protein remains unknown.

Product Categories/Family for anti-RUTBC1 antibody

Antibodies; KIAA; orf

References

Vasan, R.S., et al. JAMA 302(2):168-178(2009). Ishibashi, K., et al. Genes Cells 14(1):41-52(2009). Yang, H., et al. Genomics 90(2):249-260(2007). Stelzl, U., et al. Cell 122(6):957-968(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 148612829
• NCBI GeneID: 9905
• NCBI Accession #: NP_001091979.1; NP_055668.2
• NCBI GenBank Nucleotide #: NM_001098509.1
• UniProt Accession #: O43147; Q49AC2; Q6ZUY2; Q8IXU4; A5LGW2; B4DH69
• Molecular Weight: 110,858 Da
• NCBI Official Full Name: small G protein signaling modulator 2 isoform 2
• NCBI Official Synonym Full Names: small G protein signaling modulator 2
• NCBI Official Symbol: SGSM2
• NCBI Official Synonym Symbols: RUTBC1
• NCBI Protein Information: small G protein signaling modulator 2; RUN and TBC1 domain containing 1; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2 protein
• UniProt Protein Name: Small G protein signaling modulator 2
• UniProt Gene Name: SGSM2
• UniProt Synonym Gene Names: KIAA0397; RUTBC1
• UniProt Entry Name: SGSM2_HUMAN

Uniprot Description

SGSM2: Belongs to the RUTBC family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 17p13.3

Molecular Function: Rab GTPase binding