Western Blot (WB)
(Western blot analysis of SGSM2 in human cerebellum tissue lysate with SGSM2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide)
Rabbit SGSM2 Polyclonal Antibody | anti-SGSM2 antibody
SGSM2 Antibody
Gene Names
SGSM2; RUTBC1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunofluorescence
Purity
SGSM2 Antibody is affinity chromatography purified via peptide column.
Synonyms
SGSM2; Polyclonal Antibody; SGSM2 Antibody; RUTBC1; KIAA0397; Small G protein signaling modulator 2; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2; anti-SGSM2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Multiple isoforms of SGSM2 are known to exist. SGSM2 antibody is predicted to not cross react with other SGSM family proteins.
Purity/Purification
SGSM2 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1051
Applicable Applications for anti-SGSM2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
SGSM2 antibody can be used for detection of SGSM2 by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
SGSM2 antibody was raised against an 18 amino acid synthetic peptide near the center of human SGSM2.
Buffer
SGSM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SGSM2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of SGSM2 in human cerebellum tissue lysate with SGSM2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide)
Western Blot (WB)
(Western blot analysis of SGSM2 in human cerebellum tissue lysate with SGSM2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide)
Immunofluorescence (IF)
(Immunofluorescence of SGSM2 in human brain tissue with SGSM2 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of SGSM2 in human brain tissue with SGSM2 antibody at 20 μg/mL.)
Related Product Information for anti-SGSM2 antibody
SGSM2 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
116 kDa
NCBI Official Full Name
small G protein signaling modulator 2 isoform 1
NCBI Official Synonym Full Names
small G protein signaling modulator 2
NCBI Official Symbol
SGSM2
NCBI Official Synonym Symbols
RUTBC1
NCBI Protein Information
small G protein signaling modulator 2; RUN and TBC1 domain containing 1; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2 protein
UniProt Protein Name
Small G protein signaling modulator 2
Protein Family
UniProt Gene Name
SGSM2
UniProt Synonym Gene Names
KIAA0397; RUTBC1
UniProt Entry Name
SGSM2_HUMAN
Uniprot Description
SGSM2: Belongs to the RUTBC family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein regulator, misc.
Chromosomal Location of Human Ortholog: 17p13.3
Molecular Function: Rab GTPase binding
Research Articles on SGSM2
Similar Products
Product Notes
The SGSM2 sgsm2 (Catalog #AAA151080) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SGSM2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SGSM2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). SGSM2 antibody can be used for detection of SGSM2 by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the SGSM2 sgsm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGSM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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