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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using RUSC1 Polyclonal Antibody at dilution of 1:90(×200))

Rabbit anti-Human RUSC1 Polyclonal Antibody | anti-RUSC1 antibody

RUSC1 Polyclonal Antibody

Gene Names
RUSC1; NESCA
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
RUSC1; Polyclonal Antibody; RUSC1 Polyclonal Antibody; DKFZp761A1822; Nesca; New molecule containing SH3 at the carboxy terminus; RUN and SH3 domain containing 1; RUN and SH3 domain containing protein 1; RUSC 1; anti-RUSC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.56mg/mL (varies by lot)
Sequence Length
902
Applicable Applications for anti-RUSC1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:300
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human RUSC1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using RUSC1 Polyclonal Antibody at dilution of 1:90(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using RUSC1 Polyclonal Antibody at dilution of 1:90(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RUSC1 Polyclonal Antibody at dilution of 1:90(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RUSC1 Polyclonal Antibody at dilution of 1:90(×200))
Related Product Information for anti-RUSC1 antibody
Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.
Product Categories/Family for anti-RUSC1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
RUN and SH3 domain-containing protein 1 isoform a
NCBI Official Synonym Full Names
RUN and SH3 domain containing 1
NCBI Official Symbol
RUSC1
NCBI Official Synonym Symbols
NESCA
NCBI Protein Information
RUN and SH3 domain-containing protein 1
UniProt Protein Name
RUN and SH3 domain-containing protein 1
UniProt Gene Name
RUSC1
UniProt Synonym Gene Names
NESCA; Nesca
UniProt Entry Name
RUSC1_HUMAN

Uniprot Description

RUSC1: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q21-q22

Cellular Component: microtubule cytoskeleton; Golgi apparatus; postsynaptic membrane; microtubule; postsynaptic density; cytoplasmic membrane-bound vesicle; early endosome; cytoplasm; cytoplasmic vesicle; cell junction; nucleus

Molecular Function: protein binding; SH3/SH2 adaptor activity; actin binding

Biological Process: protein polyubiquitination; positive regulation of signal transduction

Research Articles on RUSC1

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Product Notes

The RUSC1 rusc1 (Catalog #AAA2560927) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RUSC1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RUSC1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:300 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the RUSC1 rusc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RUSC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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