Rabbit anti-Human RUNDC3A Polyclonal Antibody | anti-RUNDC3A antibody

RUNDC3A, ID (RUNDC3A, RAP2IP, RPIP8, RUN domain-containing protein 3A, Rap2-interacting protein 8) (Biotin)

Cat. Num. AAA6344427

• Gene Names: RUNDC3A; RPIP8; RAP2IP; RPIP-8
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RUNDC3A; Polyclonal Antibody; ID (RUNDC3A; RAP2IP; RPIP8; RUN domain-containing protein 3A; Rap2-interacting protein 8) (Biotin); Rap2-interacting protein 8; anti-RUNDC3A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-RUNDC3A antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: RUNDC3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-157 amino acids from the Central region of human RUNDC3A.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(RUNDC3A Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RUNDC3A antibody detected the RUNDC3A protein (arrow).)

Related Product Information for anti-RUNDC3A antibody

RUNDC3A may act as an effector of RAP2A in neuronal cells (By similarity).

Product Categories/Family for anti-RUNDC3A antibody

Antibodies; Proteins

References

Lamesch, P., et al. Genomics 89(3):307-315(2007). Lim, J., et al. Cell 125(4):801-814(2006). Janoueix-Lerosey, I., et al. Eur. J. Biochem. 252(2):290-298(1998).

NCBI and Uniprot Product Information

• NCBI GI #: 221307578
• NCBI GeneID: 10900
• NCBI Accession #: NP_001138297.1
• NCBI GenBank Nucleotide #: NM_001144825.1
• UniProt Accession #: Q59EK9; O15483; O60651; Q7Z3S2; Q9UF50; B2R974
• Molecular Weight: 49,747 Da
• NCBI Official Full Name: RUN domain-containing protein 3A isoform 1
• NCBI Official Synonym Full Names: RUN domain containing 3A
• NCBI Official Symbol: RUNDC3A
• NCBI Official Synonym Symbols: RPIP8; RAP2IP; RPIP-8
• NCBI Protein Information: RUN domain-containing protein 3A; RaP2 interacting protein 8; rap2-interacting protein 8
• UniProt Protein Name: RUN domain-containing protein 3A
• Protein Family: RUN domain-containing protein
• UniProt Gene Name: RUNDC3A
• UniProt Synonym Gene Names: RAP2IP; RPIP8; RPIP-8
• UniProt Entry Name: RUN3A_HUMAN

Uniprot Description

RPIP8: May act as an effector of RAP2A in neuronal cells. Belongs to the RUNDC3 family. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: plasma membrane; cytosol

Molecular Function: peptide hormone receptor binding; guanylate cyclase activator activity

Biological Process: small GTPase mediated signal transduction; positive regulation of guanylate cyclase activity